Generic Name
MercaptopurinePacks Price
- Tab 50 mg: 30: 210.12: 247.20
Mercaprine
Therapeutic Group
Anti-neoplasticsIndication Dosage
Mercaptopurine is a medication primarily indicated for the treatment of acute lymphoblastic leukemia (ALL) and Crohn's disease. In patients with ALL, it is used as part of a combination therapy to suppress the growth of cancerous cells in the bone marrow. In cases of Crohn's disease, Mercaptopurine helps to reduce inflammation in the gastrointestinal tract and manage symptoms associated with this chronic inflammatory condition.
Acute Lymphoblastic Leukaemias, Chronic Myeloid Leukaemia:
- Adult: Initially 2.5 Mg/kg Daily, Adjusted According to Toresponse, Alternatively Initially 50-75 Mg/m2 Daily, Adjusted According To Response
Content
- Tab 50mg: Mercaptopurine 50mg.
Pregnancy
Contraindicated In Pregnancy.
Stability
- Antimetabolite
Contra Indications
- Severe Liver Disease, Severe Bone Marrow Suppression, Absent Thiopurine Methyltransferase Activity; Consider Pre-treatment Screening
Precautions
- Severe Liver Disease, Severe Bone Marrow Suppression, Absent Thiopurine Methyltransferase Activity; Consider Pre-treatment Screening
Lactation
- Contraindicated. Discontinue Breast-feeding
Side Effects
- Alopecia
- Anorexia
- Bone-marrow Suppression
- Hepatotoxicity
- Hyperuricaemia
- Myelosuppression
- Liver Toxicitynausea
- Oral Mucositis
- Thromboembolism
- Tumourlysis Syndrome
- Vomiting
- Rare: Pancreatitis
- Transient Oligospermia
- Intestinal Ulceration
- Lymphoma
Available Brands
Author
Shahid Arif