Neo-Pyrolate

Therapeutic Group

Indication Dosage

Glycopyrrolate and neostigmine are medications commonly used in combination to manage various medical conditions. Glycopyrrolate acts as an anticholinergic agent, helping to reduce excessive salivation and prevent unwanted muscle contractions. Neostigmine, on the other hand, is a cholinergic medication that increases the levels of acetylcholine, a neurotransmitter, to improve muscle function and neuromuscular transmission. Together, they are primarily indicated for the reversal of neuromuscular blockade induced by non-depolarizing neuromuscular blocking agents during surgical procedures or in critical care settings.

Reversal Of Residual Non-depolarising (competitive) Neuromuscular Block: 

By IV Inj: 

• Adults: 1-2 Ml Over A Period Of 10-30 Sec; Alternatively 0.02 Ml/kg Intravenously Over A Period Of 10-30 Sec. 
• Children: 0.02 Ml/kg Iv Over A Period Of 10-30 Sec. Alternatively, Dilute To 10 Ml With Water For Injection Or 0.9% Sodium Chloride Injection And Administer 1 Ml:./5 Kg Body Weight. These Doses May Be Repeated If Adequate Reversal Of Neuromuscular Blockade Is Not Achieved, Max Dose 2 Ml.

Content

Pregnancy

Risk Cannot Be Ruled Out.

Stability

Contra Indications

Precautions

Lactation

Side Effects