Generic Name
OcrelizumabPacks Price
- Inj 300 mg/10 ml: 1 vial: 433500.00:510000.00
Ocrevus
Therapeutic Group
ImmunosuppressantsIndication Dosage
Primary Progressive Multiple Sclerosis, Relapsing Forms Of Multiple Sclerosis:
By IV Infusion:
- Adult: Initially 300 Mg, Then 300 Mg After 2 Weeks; Maintenance 600 Mg Every 6 Months; A Minimum Interval Of 5 Months Should Be Maintained Between Each Maintenance Dose
Content
- Inj: Ocrelizumab 30mg Per 1 ml; 300mg /10ml Concentrate For Solution For Infusion Vials
Pregnancy
Contraindicated, Use Contraceptives During Treatment And For 12 Months After The Last Dose
Stability
- Immunosuppressant
- Anti-lymphocyte Monoclonal Antibodies
Contra Indications
- Patients With Active Hepatitis B Virus Infection And In Patients With A History Of Life-threatening Infusion Reaction To Ocrelizumab, Active Infection, Active Malignancies, Severely Immunocompromised Patients
Precautions
- Patients With Active Hepatitis B Virus Infection And In Patients With A History Of Life-threatening Infusion Reaction To Ocrelizumab, Active Infection, Active Malignancies, Severely Immunocompromised Patients
Lactation
- Contraindicated Discontinue Breast-feeding
Side Effects
- Anaphylactic Reaction
- Alopecia
- Anaemia
- Arthralgia
- Asthenia
- Constipation
- Diarrhea
- Cough
- Cytokine Release Syndrome
- Depression
- Dyspnea
- Fever
- Flushing
- Headache
- Hypertension
- Hypotension
- Infusion Related Reaction
- Leucopenia
- Nausea
- Neutropenia
- Pruritus
- Sweat Changes
- Tachycardia
- Thrombocytopenia
- Tumour Lysis Syndrome
- Vomiting
- Rare: Progressive Multifocal Leukoencephalopathy
- Hepatitis B Reactivation
Author
Shahid Arif