Generic Name
Crisantaspase (l-asparaginase)Packs Price
- Inj 10000 IU: 1 Vial: 2335.80: 2748.00
Perginase
Therapeutic Group
Anti-neoplasticsIndication Dosage
Indication:
Crisantaspase, also known as l-asparaginase, is a medication used to treat certain types of cancer. It is specifically used to help control leukemia, a type of blood cancer, by reducing the levels of a substance called asparagine in the body, which leukemia cells need to grow. By lowering asparagine, Crisantaspase can help slow down or stop the growth of leukemia cells, improving the chances of recovery for patients with this type of cancer.
Dosage:
Acute Lymphocytic Leukaemia:
By IV Inj:
- Adults & Children: 1000 Iu/kg Every Day X 10 Days Beginning Day 22 Of Treatment Period Or By Im, 6000 Iu/m2 On Days 4,7,10,13,16,19,22,25, & 28.
Content
- Inj: L-asparaginase 10,000 Iu; Vial.
Pregnancy
Contraindicated Or Not Recommended
Stability
- Protein Synthesis Inhibitor Antineoplastic
Contra Indications
- Serious Thrombosis, Pancreatitis, History Of Pancreatitis Related To Asparaginase Therapy
Precautions
- Serious Thrombosis, Pancreatitis, History Of Pancreatitis Related To Asparaginase Therapy
Lactation
- Contraindicated. Discontinue Breast-feeding.
Side Effects
- Coagulation Disorders
- Confusion
- Convulsions
- Diarrhoea
- Dizziness
- Drowsiness
- Headache
- Lethargy
- Liver Dysfunction
- Neurotoxicity
- Pancreatitis
- Anaphylaxis
- Changes In Blood Lipids
- Hyperglycaemia
- Alopecia
- Bone-marrow Suppression
- Extravasation
- Hyperuricaemia
- Nausea
- Oral Mucositis
- Thromboembolism
- Tumourlysis Syndrome
- Vomiting
- Depression
- Myalgia
- Hypofibrinogenemia
- Decrease In Number Of Clotting Factors
- Hypotension
- Angioedema
- Bronchospasm
- Increased Bilirubin
- Transaminases And Alkaline Phosphatase
- Azotemia
- Stomafifits
Author
Shahid Arif