Generic Name
Rifampicin, Isoniazid, Ethambutol And PyrazinamidePacks Price
- Tab 150/75/275/400 mg(055531): 8x10: 755.25: 888.53
Pire+4
Therapeutic Group
Anti-mycobacterials (Anti-tuberculosis)Indication Dosage
Initial Treatment Of Tuberculosis:
- Adult (body weight 30-39 Kg): 2 Tablets Daily For 2 Months (initial Phase);
- (body-weight 40-54 Kg): 3 Tablets Daily For2 Months (initial Phase);
- (body-weight 55-69 Kg): 4 Tablets Daily For2 Months (initial Phase);
- (body-weight 70 Kg And Above): 5 Tablets Daily For 2 Months (initial Phase)
Content
- Tab 120 /60 /225 /300mg: Rifampicin 120mg, Isoniazid 60mg, Ethambutol 225mg, Pyrazinamide 300mg.
- Tab 150 /75 /275 /400mg: Rifampicin 150mg, Isoniazid 75mg,ethambutol 275mg, Pyrazinamide 40
Pregnancy
Risk Cannot Be Ruled Out.
Stability
- Ethambutol
- Isonicotinic Acid Derivative
- Nicotinic Acid Derivative
- Rifamycin
Contra Indications
- Liver Disease, Previous Hypersensitivity To Any Rifamycin, Patients With Previous Isoniazid Associated Hepatic Injury Or Other Severe Adverse Reactions With Isoniazid, Hypersensitivity To Ethambutol, Optic Neuritis.
Precautions
- Liver Disease, Previous Hypersensitivity To Any Rifamycin, Patients With Previous Isoniazid Associated Hepatic Injury Or Other Severe Adverse Reactions With Isoniazid, Hypersensitivity To Ethambutol, Optic Neuritis.
Lactation
- Caution Advised or Effect Undetermined.
Side Effects
- Anaphylactoid Reactions
- Heartburn
- Epigastric Dis-tress
- Anorexia
- Nausea
- Vomiting
- Diarrhoea
- Sore Mouth
- Rash
- Pruritus
- Urticaria
- Eosinophilia
- Thrombocytopenia
- Muscular Weakness
- Pain In Extremities
- Visual Disturbances
- Haemoglobinuria
- Hematuria
- Menstrual Disturbances
- Peripheral Neuropathy
- Elevated Sgot
- Sgpt
- Sgopt
- Optic Neuritis (related To Dose And Duration Of Treatment)
- Abdominal Distress
- Fever
- Malaise Headache Diz-ziness
- Elevated Serum Uric Acid Level
- Hepatitis Which Can Be Minimized By Dose Adjustment.
Available Brands
Author
Shahid Arif