Prolfer
Generic Name
Interferon Alfa-2b
Packs Price
- Inj 3 MIU: 1 Amp: 724.80:852.71
Company
Zafa
Therapeutic Group
Immunomodulators
Indication Dosage
Interferon Alfa-2b is a medication used to treat certain viral infections, such as hepatitis B and C, as well as some types of cancer, like melanoma and certain leukemias. It helps your body's immune system fight these infections and diseases.
Chronic Active Hepatitis B In Patients Positive For Hbv-DNA, In Combination With Ribavirin, Unless Intolerant Or Contraindicated:
By Sc Inj:
- Adults: 2.5-5 Mega Units/m23 Times Per Week For 4-6 Months. Increase Dose After 1 Month If Response Not Adequate, Discontinue After 3-4 Months If No Improvement.
Chronic Hepatitis C In Patients Positive For Hcv Antibodies Or Hcv-rna With Elevated Alt Levels:
By Sc Inj Or IM Inj:
- Adult: In Combination With Tribavirin, In Relapsed Patients Who Previously Responded To Interferon Alfa, 4.5 Mega Units 3 Times Per Week For 6 Months; In Interferon Alfa Naive Patients, 3-4.5 Mega Units 3 Times Per Week For Minimum 6 Months;
Hepatitis C Monotherapy:
By Sc Inj Or IM Inj:
- Adult: Initially 3-6 Mega Units 3 Times Per Week For 6 Months; Maintenance, 3 Mega Units 3 Times Per Week For A Further 6 Months.
Hairy Cell Leukaemia:
By Sc Inj Or IM Inj:
- Adults: Induction Dose, 3 Mega Units Daily For 16-24 Weeks; Maintenance Dose, 3 Mega Units 3 Times Per Week; Max 3 Mega Units.
Aids-related Kaposi-s Sarcoma:
By Sc Inj Or IM Inj:
- Adults: Induction Dose36 Mega Units Daily For 10-12 Weeks; Maintenance Dose, 36 Mega Units 3 Times Per Week. An Escalating Schedule Of 3, 9, And 18 Million IU daily For 3 Days Followed By 36 Mega Units Daily For The Remainder Of The 10 To 12 Week Induction Period Also Has Been Beneficial With Some Amelioration Of The Acute Toxicity In Some Patients.
Chronic Myelogenous Leukaemia:
By Sc Inj Or IM Inj:
- Adults: Induction Dose, 9 Mega Units Daily Gradually Increasing The Dose Over The First Week Of Administration From 3 Mega Units Daily For 3 Days To 6 Mega Units Daily For 3 Days To The Target Dose Of 9 Mega Units Daily For Duration Of The Treatment Period.
Recurrent Or Metastatic Renal Cell Carcinoma, Progressive Cutaneous T-cell Lymphoma, Follicular Non-hodgkin's Lymphoma, Adjunct To Surgery In Malignant Melanoma:
By Sc Inj:
- Adults: Consult Product Literature
Content
- Inj 3 Miu /5 Miu /10 Miu /18 Miu /25 Miu /30 Miu /60 Miu: Interferon Alfa-2b (rbe) 3 Miu /5 Miu /10 Miu /18 Miu /25 Miu /30 Miu /60 Miu: Powder In Vial. Inj.
- Inj 18 Miu /30 Miu /60 Miu: Interferon Alfa-2b
Pregnancy
Avoid, Use Only When No Safer Alternative Exists For A Serious Problem.
Stability
- Single-subtype Recombinant
Contra Indications
- Severe Renal, Hepatic Or Myeloid Dysfunction, Epilepsy Or Cns Impairment, Cardiac Disease, Decompensated Hepatic Disease, Liver Cirrhosis.
Precautions
- Severe Renal, Hepatic Or Myeloid Dysfunction, Epilepsy Or Cns Impairment, Cardiac Disease, Decompensated Hepatic Disease, Liver Cirrhosis.
Lactation
Side Effects
- Anorexia
- Diarrhoea
- Influenza-like Symptoms
- Lethargy
- Nausea
- Alopecia
- Arrhythmias
- Cardiovascular Problems
- Coma (usually With High Doses In Elderly)
- Confusion
- Depression
- Hepatotoxicity
- Hyperglycaemia
- Hypersensitivity Reactions
- Hypertension
- Hypertriglyceridaemia
- Hypotension
- Myelosuppression
- Nephrotoxicity
- Ocular Side-effects
- Palpitation
- Psoriasis Form
- Rash
- Seizures (usually With High Doses In The Elderly)
- Suicidal Behavior
- Thyroid Abnormalities