Anti-D (Rh0) Immunoglobulin is used to prevent Rh sensitization during pregnancy. It's given to Rh-negative mothers after childbirth if their baby is Rh-positive to avoid future pregnancy complications.
To Rhesus-negative Woman For Prevention Of Rh0 (d) Sensitisation, Following Birth Of Rhesus-positive Infant, Or Following Any Potentially Sensitizing Episode (e.g. Stillbirth, Abortion, Amniocentesis) 20-28 Weeks' Gestation:
By Deep IM Inj:
Females Of Childbearing Potential: 1 Vial To Be Administered Immediately Or Within 72 Hours Of Childbirth; For Transplacental bleeding of Over 4ml Fetal Red Cells, Extra100-125 Units Per Ml Fetal Red Cells, Subcutaneous Route Used For Patients With Bleeding Disorders.
By IV Inj:
Lyophilized Incomplete Anti-d Sera With Negative 1 Gm-anti-d At Least 300 Mcg: Females: Within 84 Hr Of Every Termination Of Pregnancy, Abortion Or Delivery To Rh-negative Women With Rh-positive Baby. The Adjustment Of Dose Can Be Made As 1 Amp Of Anti Rh0 300 For Every 30-50 Ml, Transfused Blood. For Rh-negative Female Infant Of Rh-positive Mothers, One-Third Of Adult Dose Just After Delivery To Rhesus-negative Woman For Prevention Of Rh0 (d) Sensitisation, Antenatal Prophylaxis
By Deep IM Inj:
Females Of Childbearing Potential: 1vial To Begiven At Weeks 28 And 34 Of Pregnancy, If Infant Rhesus-positive, A Further Dose Is Still Needed Immediately Or Within 72 Hours Of Delivery, Subcutaneous Route Used For Patients With Bleeding Disorders
Content
Inj: Per Vial: Rho (d) Immune Globulin (human) Equiv To 50 Mcg And 300 Mcg;
Inj: Lyophilized Incomplete Anti-d Sera With Negative 1gm-anti-d At Least 300 Mcg
Inj: Per 2 ml Vial: Immunoglobulin.
Pregnancy
Consult with Doctor Or Caution Advised
Stability
Immune Globulin
Contra Indications
Treatment Of Idiopathic Thrombocytopenia Purpura In Rhesus Negative Patients, Treatment Of Idiopathic Thrombocytopenia Purpura In Splenectomised Patients
Precautions
Treatment Of Idiopathic Thrombocytopenia Purpura In Rhesus Negative Patients, Treatment Of Idiopathic Thrombocytopenia Purpura In Splenectomised Patients