Therapeutic Group

Indication Dosage

Tuberculosis, In Combination With Other Drugs (intermittent Supervised 6-month Treatment): 

• Adult: 600-900 Mg 3 Times A Week For 6 Months (initial And Continuation Phases) 
• Children: 15 Mg/kg 3 Times A Week (max. Per Dose 900 Mg) For 6 Months (initial And Continuation Phases) 

Tuberculosis, In Combination With Other Drugs (standard Unsupervised 6-month Treatment): 

• Adult (body-weight Up To 50 Kg): 450 Mg Once Daily For 6 Months; (body-weight 50 Kg And Above): 600 Mg Once Daily For 6 Months (initial And Continuation Phases) 
• Children: 15 Mg/kg Once Daily For 6 Months (initial And Continuation Phases); Maximum 450 Mg Per Day For Less Than 50 Kg Body Weight, For Above 50 Kg Body Weight Max 600 Per Day 

Prevention Of Tuberculosis In Susceptible Close Contacts Or Those Who Have Become Tuberculin Positive (with Or Without Isoniazid): 

• Adult & Children Above 12 Yrs: (body-weight Up To 50 Kg): 450 Mg Daily For 3 Months; (body-weight 50 Kg And Above): 600 Mg Daily For3 Months With Isoniazid Or For 6 Months Without Isoniazid 
• Children 1 Month-11 Yrs: (body-weight Up To 50 Kg): 15 Mg/kg Daily, Maximum 450 Mg Per Day For 3 Months With Isoniazid Or For 6 Months Without Isoniazid; (body-weight 50 Kg And Above): 15 Mg/kg Daily, Maximum 600 Mg Per Day For 3 Months With Isoniazid Or For 6 Months Without Isoniazid 

Prevention Of Secondary Case Of Haemophilus Influenza Type B Disease: 

• Adult & Children Above 12 Yrs: 600 Mg Once Daily For 4 Days 
• Children 1-2 Months: 10 Mg/kg Once Daily For 4 Days; 
• 3 Months - 11 Yrs: 20 Mg/kg Once Daily (max. Per Dose 600 Mg) For 4 Days 

Prevention Of Secondary Case Of Meningococcal Meningitis: 

• Adult & Children Above 12 Yrs: 600 Mg Every 12 Hours For 2 Days 
• Children 1-11 Months: 5 Mg/kg Every 12 Hours For 2 Days; 
• 1-11 Yrs: 10 Mg/kg Every 12 Hours (max. Per Dose 600 Mg), For 2 Days 

Brucellosis, Legionnaires Disease, and Serious Staphylococcal Infections, in Combination With Other Antibacterials: 

• Adult: 0.6-1.2 G Daily In 2-4 Divided Doses 
• Children 1-11 Months: 5-10 Mg/kg Twice Daily; 
• 1-17 Years: 10 Mg/kg Twice Daily (max. Per Dose600 Mg) 

Endocarditis In Combination With Other Drugs: 

• Adult: 0.6-1.2 G Daily In 2-4 Divided Doses

Content

Pregnancy

Caution Advised, Use Only If Potential Benefit Outweighs Risk

Stability

Contra Indications

Precautions

Lactation

Side Effects