Septran
Generic Name
Co-trimoxazole
Packs Price
- SuspDS 80/400 mg(000875): 50 ml: 55.36: 65.13
- SuspPaeds 40/200 mg(000384): 50 ml: 40.93: 48.15
- Tab 80/400 mg (000388): 400: 1153.35: 1356.88
- TabDS 160/800 mg(004926): 100: 541.25: 636.77
Company
GSK
Therapeutic Group
Sulfonamides And Trimethoprim
Indication Dosage
Treatment Of Susceptible Infections of Respiratory Tract, Gastro-intestinal, Urinary Tracts, Skin & Soft-tissues:
Oral:
- Adult & Children Above 12 Years: 960 Mg Twice Daily
- Children 6 Weeks - 5 Months: 120 Mg Twice Daily, Alternatively 24 Mg/kg Twice Daily;
- 6 Months - 5 Yrs: 240 Mg Twice Daily, Alternatively 24 Mg/kg Twice Daily;
- 6 - 11 Yrs: 480 Mg Twice Daily, Alternatively24 Mg/kg Twice Daily
By IV Infusion:
- Adult: 960 Mg Every 12 Hours, Increased To 1.44 G Every12 Hours, Increased Dose Used In Severe Infection
Treatment Of Pneumocystis Jirovecii (pneumocystis Carinii) Infections:
Oral Or By IV Infusion:
- Adult: 120 Mg/kg Daily In 2-4 Divided Doses For 14-21 Days. Prophylaxis: 960 Mg Once Daily (oral), Reduced If Not Tolerated To 480 Mg Once Daily, Alternatively 960 Mg Once Daily On Alternate Days, 3 Times Weekly
- Children: 120 Mg/kg Daily In 2-4 Divided Doses For 14-21 Days, Oral Route Preferred For Children. Prophylaxis: 450 Mg/m2 Twice Daily (max. Per Dose 960 Mg Twice Daily) For 3 Days Of The Week (either Consecutively Or On Alternate Days)
Content
- Tab 80 /400mg: Trimethoprim 80mg, Sulfamethoxazole 400mg.
- Tab 160 /800mg: Trimethoprim 160mg, Sulfamethoxazole 800mg.
- Susp 40 /200mg: Per 5 ml: Trimethoprim 40mg, Sulfamethoxazole 200
Pregnancy
Contraindicated In Pregnancy.
Stability
- Folic Acid Inhibitor
- Sulphonamide
Contra Indications
- Neonates, Severe Renal Or Hepatic Insufficiency, Blood Dyscrasias.
Precautions
- Neonates, Severe Renal Or Hepatic Insufficiency, Blood Dyscrasias.
Lactation
- Contraindicated or Not Recommended.
Side Effects
- Abdominal Discomfort
- Diarrhoea
- Headache
- Hyperkalaemia
- Nausea
- Rash
- Vomiting
- Glossitis
- Blood Dyscrasias
- Folate Deficiency
- Liver Changes. Rarely: Erythema Multiforme
- Lyell Syndrome
- Exfoliative Dermatitis
- Stevens-johnson Syndrome
- Convulsions
- Peripheral Neuritis
- Ataxia
- Granulocytosis And Bone Marrow Depression