Simva
Generic Name
Simvastatin
Packs Price
- Tab 10 mg(027207): 20: 207.73: 244.39
- Tab20 mg(027204): 20: 336.60: 396.00
Company
Nabiqasim
Therapeutic Group
Lipid Modifying Agents
Indication Dosage
Primary Hypercholesterolaemia, Or Combined (mixed) Hyperlipidaemia:
- Adult: 10-20 Mg Once Daily At Night, Then Increased If Necessary Up To 80 Mg Once Daily, Adjusted At Intervals Of At Least4 Weeks, 80 Mg Dose Only For Those With Severe Hypercholesterolaemia And At High Risk Of Cardiovascular Events
- Children 5-10 Yrs: Initially 10 Mg At Night Increased, If Necessary, At Intervals Of At Least 4 Week To Max 20 Mg At Night; 10-18 Yrs: Initially 10 Mg At Night Increased, If Necessary, At Intervals Of At Least 4 Wk To Max 40 Mg At Night.
Homozygous Familial Hypercholesterolaemia:
- Adult: Initially 40 Mg Once Daily At Night, Then Increased If Necessary Up To 80 Mg Once Daily, Adjusted At Intervals Of At Least 4 Weeks, 80 Mg Dose Only For Those With Severe Hypercholesterolaemia And At High Risk Of Cardiovascular Events
Prevention Of Cardiovascular Events In Patients With Atherosclerotic Cardiovascular Disease Or Diabetes Mellitus:
- Adult: Initially 20-40 Mg Once Daily At Night, Increased If Necessary Up To 80 Mg Once Daily, Adjusted At Intervals Of At Least 4 Weeks,
Content
- Tab 10mg /20mg /40mg /80mg: Simvastatin 10mg /20mg /40mg /80mg.
Pregnancy
Contraindicated In Pregnancy.
Stability
Contra Indications
- Active Liver Disease, Pregnancy
Precautions
- Active Liver Disease, Pregnancy
Lactation
Side Effects
- Constipation
- Flatulence
- Headache
- Asthenia
- Nausea
- Dyspepsia
- Abdominal Pain Diarrhoea
- Rash
- Alopecia
- Dizziness
- Muscle Cramps
- Myalgia
- Pancreatitis
- Paraesthesia
- Peripheral Neuropathy
- Anaemia
- Hepatitis
- Jaundice.
- Rare: Rhabdomyolysis
- Myopathy; Measure Creatine Phosphokinase Levels; Withdraw Therapy If Markedly Raised.