Suppression Of Inflammatory And Allergic Disorders, Cerebral Oedema Associated With Malignancy:
By IM Inj, Or By Slow IV Infusion:
Adult: Initially 10-500 Mg;
Children 1 Month-18 Yrs: 0.5-1.7 Mg/kg Daily In 2-4 Divided Doses Depending On Condition And Response.
Treatment Of Graft Rejection Reactions:
By IV Infusion:
Adult: Up To 1 G Daily For Up To 3 Days
By IV Inj:
Children 1 Month -18 Yrs: 10-20 Mg/kg Or 400-600 Mg/square Meter (max. 1 Gm), Once Daily For 3 Days.
Anti-inflammatory Or Allergic Disorder, Immunosuppressive:
By IM Inj:
Adult: 10-80 Mg/ Day Once Daily.
By IV Inj:
Adult: 10-40 Mg Over A Period Of Several Minutes And Repeated IV or Im At Intervals Depending On Clinical Response; When High Dosages Are Needed, Give 30 Mg/kg Over A Period of 30 Minutes Or More And May Be Repeated Every 4-6 Hr For 48 Hr.
Asthma Exacerbations, Including Status Asthmaticus:
By IV Inj:
Adult: 40-80 Mg/day In 1- 2 Divided Doses Until Peak Expiratory Flow Is 70% Of Predicted Or Personal Best.
Dermatomyositis, Polymyositis:
By IV Inj:
Adult: 1 Gm/day For 3-5 Days For Severe Muscle Weakness, Followed By Conversion To Oral Prednisone.
Lupus Nephritis:
By IV Inj:
Adult: 0.5-1 Gm/day For 3 Days.
Pneumocystis Pneumonia In Aids Patients:
By IV Inj:
Adult: 30 Mg Twice Daily For 5 Days, Then 30 Mg Once Daily For 5 Days, Then 15 Mg Once Daily For 11 Days.
Severe Erythema Multiforme, Lupus Nephritis, Systemic Onset Juvenile Idiopathic Arthritis:
By IV Inj:
Children: 1 Month -18 Yrs: 10-30 Mg/kg (max 1 Gm) Once Daily Or On Alternate Days For Up To 3 Doses.
Content
Inj 40mg /125mg /500mg /1gm: Methylprednisolone (as Sodium Succinate) 40mg /12 5mg /500mg / 1gm; Powder In Vials, And Solvent.
Pregnancy
Caution Advised
Stability
Glucocorticoid
Contra Indications
Systemic Fungal Infections Unless Specific Anti-infective Therapy Is Used, Head Injury, Stroke.
Precautions
Systemic Fungal Infections Unless Specific Anti-infective Therapy Is Used, Head Injury, Stroke.
Lactation
Caution Advised
Side Effects
Endocrine Irregularities Including Menstrual Problems