Taxotere
Generic Name
Docetaxel
Packs Price
- Inf 20 mg/1 ml(066089): 1 Vial: 7140.00: 8400.0
- Inf 80 mg/4 ml(066090): 1 Vial: 17850.00: 21000.00
Company
SANOFI-AVENTIS
Therapeutic Group
Anti-neoplastics
Indication Dosage
Indication:
Docetaxel is a medication used to treat various types of cancer, including breast cancer, lung cancer, prostate cancer, and certain types of stomach, head, and neck cancers. It works by slowing the growth and spread of cancer cells in the body and is typically used when other treatments have not been effective. Your doctor may prescribe Docetaxel as part of your cancer treatment plan to help shrink tumors and improve your overall health.
Dosage:
Locally Advanced Or Metastatic Breast Cancer Resistant Or Refractory To Cytotoxic Therapy Where An Anthracycline Is Indicated:
By IV Infusion:
- Adults: 60-100 Mg/m2 Iv Over 1 Hr Every 3 Week. Dosage Adjustment May Be Required.
Adjuvant Treatment Of Operable Node-positive And Operable Node-negative Breast Cancer (in Combination): Neutrophil Count >1500 Cells/cubic Mm: 75 Mg/m2 1 Hr After Doxorubicin 50 Mg/m2 And Cyclophosphamide 500 Mg/ M2 Every 3 Wk X 6 Courses. Dosage Adjustment May Be Required.
Non-small Cell Lung Cancer:
By IV Infusion:
- Adults: 75 Mg/m2 Iv Over 1 Hr Every 3 Week. Dosage Adjustment May Be Required.
Hormone-refractory Metastatic Prostate Cancer:
By IV Infusion:
- Adults: 75 Mg/ M2 Iv Over 1 Hr Every 3 Wk With Prednisone 5 Mg Twice Daily Dosage Adjustment May Be Required.
Initial Treatment Of Metastatic Gastric Adenocarcinoma, Including Adenocarcinoma Of The Gastro-oesophageal Junction (with Cisplatin And Fluorouracil), Induction Treatment Of Locally Advanced Squamous Cell Carcinoma of The Head And Neck (with Cisplatin And Fluorouracil):
By IV Infusion:
- Adults: (consult Product Literature Or Local Protocols)
- Children: Not Recommended.
Content
- Inj: Per 0.5 ml: Docetaxel 20mg; 0.5 ml (20mg), 2 ml (80mg), 3 ml (120mg) And Diluent.
- Inj: Per ml: Docetaxel 10mg; 2 ml (20mg), 8 ml (80mg), 16 ml (160mg).
Pregnancy
Positive Evidence Of Risk: Avoid
Stability
Contra Indications
- Previous Severe Hypersensitivity To Docetaxel. Neutrophils, Severe Liver Impairment, Acute Porphyrias
Precautions
- Previous Severe Hypersensitivity To Docetaxel. Neutrophils, Severe Liver Impairment, Acute Porphyrias
Lactation
- Contraindicated. Discontinue Breast-feeding
Side Effects
- Alopecia
- Bone-marrow Suppression
- Cystoidmacular Oedema
- Extravasation
- Fatal Respiratory Disorders
- Gi Toxicity
- Heart Failure
- Hypersensitivity Reactions
- Hyperuricaemia
- Nausea
- Oral Mucositis
- Peripheral Neurotoxicity
- Persistent Fluid Retention
- Can Be Resistant To Treatment
- Severe Skin Reactions
- Thromboembolism
- Tumourlysis Syndrome
- Vomiting