Generic Name
LapatinibPacks Price
- Tab 250 mg(084160): 70: 79987.64: 94103.10
Tykerb
Therapeutic Group
Anti-neoplasticsIndication Dosage
Lapatinib is indicated for the treatment of certain types of breast cancer. It is prescribed in combination with other medications for patients with HER2-positive metastatic breast cancer that has progressed after prior therapy. Lapatinib may also be used in combination with another medication for HER2-positive early-stage breast cancer after surgery.
Treatment Of Advanced Or Metastatic Breast Cancer In Patients With Tumours That Over Express Human Epidermal Growth Factor Receptor-2 (her2) With Hormone-receptor-negative Disease (in Combination With Trastuzumab):
- Adult: 1 G Once Daily, Or In Combination With Capecitabine,1.25 G Once Daily, Or For Postmenopausal Women, In Combination With An Aromatase Inhibitor, 1.5 G Once Daily. Counseling: Always Take At The Same Time, Either 1 hour before Or 1 hour after Food.
Content
- Tab: Lapatinib 250mg.
Pregnancy
Positive Evidence Of Risk: Avoid
Stability
- Protein Kinase Inhibitor
Contra Indications
- Hypersensitivity.
Precautions
- Hypersensitivity.
Lactation
- Contraindicated. Discontinue Breast-feeding
Side Effects
- Anorexia
- Cardiac Failure (fatal Cases Reported)
- Decreased Left Ventricular Ejection Fraction
- Diarrhoea (treat Promptly)
- Hepatotoxicity (discontinue Permanently If Severe)
- Hyperbilirubinaemia
- Malaise
- Nail Disorders
- Rash
- Interstitial Lung Disease
- Alopecia
- Bone-marrow Suppression
- Hyperuricaemia
- Nausea
- Oral Mucositis
- Respiratory Failure (including Fatal Cases)
- Thromboembolism
- Tumourlysis Syndrome
- Vomiting
Author
Shahid Arif