Vinracine
Generic Name
Vincristine Sulfate
Packs Price
- Inj 1 mg (021052): 10 Vial: 2040.00: 2270.00
- Inj2 mg(022623): 10 Vial: 2965.00: 3295.00
Company
Al Habib
Therapeutic Group
Anti-neoplastics
Indication Dosage
Vincristine Sulfate is a medication primarily used in the treatment of various types of cancer. It is commonly prescribed to patients with leukemia, lymphoma, and certain solid tumors such as neuroblastoma and Wilms tumor. Vincristine works by interfering with the growth and spread of cancer cells, making it an important component of chemotherapy regimens aimed at controlling and eradicating cancerous cells in the body.
Variety Of Cancers Including Leukaemias, Lymphomas, And Some Solid Tumours (e.g. Breast And Lung Cancer):
By IV Infusion:
- Adults: 0.4-1.4 Mg/m2, May Repeat Every week or 0.4-0.5 Mg/day Continuous Infusion For 4 Days Every 4 weeks or 0.25-0.5 Mg/ M2/d Continuous Infusion For 5 Days Every 4 Week. Also, Refer to Individual Protocols For Dosages.
- Children: <10 Kg Or Bsa<1 M2: Initial Therapy: 0.05 Mg/kg Once Weekly Then Titrate Dose; Max Single Dose: 2 Mg. 10 Kg Or Bsa>1 M2: 1-2 Mg/m2, May Repeat Once Wkly For 3-6 Week; Max Single Dose: 2 Mg.
Neuroblastoma:
By IV Infusion:
- Adult: Continuous Infusion With Doxorubicin: 1 Mg/m2/day For 72 Hr.
Content
- Inj 1mg /2mg: Vincristine Sulphate 1mg /2mg; Vial.
Pregnancy
Positive Evidence Of Risk: Avoid
Stability
Contra Indications
- Patients With Demyelinating Form Of Char-cot- Marie- Tooth Syndrome.
Precautions
- Patients With Demyelinating Form Of Char-cot- Marie- Tooth Syndrome.
Lactation
- Contraindicated. Discontinue Breast-feeding
Side Effects
- Alopecia
- Autonomic Neuropathy
- Extravasation
- Eye Disorders
- Hyperuricaemia
- Loss Of Deep Tendon Reflexes
- Motor Weakness
- Muscle Wasting
- Myelosuppression
- Neurotoxicity
- Oral Mucositis
- Ototoxicity
- Peripheral Neuropathy
- Peripheral Paraesthesia
- Severe Bronchospasm
- Severe Local Irritation
- Thromboembolism
- Tumourlysis Syndrome
- Vomiting.
- Rare: Inappropriate Secretion Of Antidiuretic Hormone
- Intestinal Necrosis
- Paralytic Ileus
- Seizures
- Urinary Retention