Generic Name
IdarubicinPacks Price
- Inj 10 mg (025276): 1 Vial: 10561.34: 12425.11
- Inj 5 mg(025275): 1 Vial: 5682.81: 6685.66
Zavedos
Therapeutic Group
Anti-neoplasticsIndication Dosage
Indarubicin is indicated for the treatment of various types of cancers, including acute myeloid leukemia (AML) in adults. It is typically used in combination with other chemotherapy drugs as part of a treatment regimen prescribed by a healthcare professional.
Acute Non-lymphocytic Leukaemias Monotherapy:
By IV Induction:
- Adult: 12 Mg/m2/day For 3 Days; Consolidation: 10-12 Mg/m2/day For 2 Days.
- Children: 10-12 Mg/m2 Every Day For 3 Day Every 3 Week.
Acute Non-lymphocytic Leukaemia In Combination Therapy:
- Adult: 10-12 Mg/m2 Daily For 3 Days
Advanced Breast Cancer After Failure Of First-line chemotherapy (not Including Anthracyclines); Monotherapy:
- Adult: 15 Mg/m2 Daily For3 Consecutive Days, Repeat Treatment Every 3-4 Weeks; Maximum 400 Mg/m2 Per Course
Acute Leukaemias, Advanced Breast Cancer After Failure Of First-line Chemotherapy (not Including Anthracyclines):
- (Consult Product Literature)
Content
- Inj: 5mg /10mg: Idarubicin 5mg /10mg; Powder In Vial.
Pregnancy
Positive Evidence Of Risk: Avoid
Stability
- Cytotoxic Anthracycline Antibiotic
Contra Indications
- Previous Treatment With Maximum Cumulative Dose Of Idarubicin Or Other Anthracycline, Recent Myocardial Infarction, Severe Arrhythmias, Severe Myocardial Insufficiency
Precautions
- Previous Treatment With Maximum Cumulative Dose Of Idarubicin Or Other Anthracycline, Recent Myocardial Infarction, Severe Arrhythmias, Severe Myocardial Insufficiency
Lactation
- Contraindicated. Discontinue Breast-feeding
Side Effects
- Abdominal Pain
- Cardiacdisorders
- Diarrhoea
- Haemorrhage
- Rash
- Red Pigmentation Of The Urine
- Nail & Skin Hyperpigmentation
- Alopecia
- Bone-marrow Suppression
- Hyperuricaemia
- Nausea
- Oral Mucositis
- Thromboembolism
- Tumourlysis Syndrome
- Vomiting
- Extravasation
Author
Shahid Arif