Ziapine-Xr
Generic Name
Quetiapine
Packs Price
- Tab 300 mg(078753): 10: 510.00: 600.00
- Tab 150 mg(078755): 10: 330.65: 389.00
Company
Araf
Therapeutic Group
Psycholeptics (Antipsychotic, Anxiolytic/Hypnotic)
Indication Dosage
Quetiapine is a medication that doctors may prescribe to help treat conditions like schizophrenia, bipolar disorder, and major depressive disorder. It can help people manage their symptoms and feel better.
Schizophrenia:
Regular Tab:
- Adult: 25 Mg Twice Daily For Day 1, Then 50 Mg Twice Daily For Day 2, Then 100 Mg Twice Daily For Day 3, Then 150 Mg Twice Daily For Day 4, Then, Adjusted According To Response, Usual Dose 300-450 Mg Daily In 2 Divided Doses, The Daily Dose Should Be Lower And Increased At Longer Interval In Elderly Patients; Maximum 750 Mg Per Day
Extended-Release Tab:
- Adult: 300 Mg Once Daily For Day 1, Then 600 Mg Once Daily For Day 2, Then, Adjusted According To Response, Usual Dose 600 Mg Once Daily, Maximum Dose Under Specialist Supervision; Maximum 800 Mg Per Day
- Elderly: Initially 50 Mg Once Daily, Adjusted According To Response Adjusted In Steps Of 50 Mg Daily
Treatment Of Mania In Bipolar Disorder:
Regular Tab:
- Adult: 50 Mg Twice Daily For Day 1, Then 100 Mg Twice Daily For Day 2, Then 150 Mg Twice Daily For Day 3, Then 200 Mg Twice Daily For Day 4, Then Adjusted In Steps Of Up To 200 Mg Daily, Adjusted According To Response, Usual Dose 400-800 Mg Daily In 2 Divided Doses, The Daily Dose Should Be Lower And Increased At Longer Interval In Elderly Patients; Maximum 800 Mg Per Day
Extended-Release Tab:
- Adult: 300 Mg Once Daily For Day 1, Then 600 Mg Once Daily For Day 2, Then, Adjusted According To Response, Usual Dose 400-800 Mg Once Daily
- Elderly: Initially 50 Mg Once Daily, Adjusted According To Response Adjusted In Steps Of 50 Mg Daily
Treatment Of Depression In Bipolar Disorder:
Regular Tab:
- Adult: 50 Mg Once Daily For Day 1, Dose To Be Taken At Bedtime, Then 100 Mg Once Daily For Day 2, Then 200 Mg Once Daily For Day 3, Then 300 Mg Once Daily For Day 4, Then, Adjusted According To Response; Usual Dose 300 Mg Once Daily, The Daily Dose Should Be Lower And Increased At Longer Interval In Elderly Patients; Maximum 600 Mg Per Day
Extended-Release Tab:
- Adult: 50 Mg Once Daily For Day 1, Dose To Be Taken At Bedtime, Then 100 Mg Once Daily For Day 2, Then 200 Mg Once Daily For Day 3, Then 300 Mg Once Daily For Day 4, Then, Adjusted According To Response; Usual Dose 300 Mg Once Daily; Maximum 600 Mg Per Day
Prevention Of Mania And Depression In Bipolar Disorder:
Regular Tab:
- Adult: Continue At The Dose Effective For The Treatment Of Bipolar Disorder And Adjust To the Lowest Effective Dose; the Usual Dose of 300-800 Mg Daily In 2 Divided Doses
Extended-Release Tab:
- Adult: Continue At The Dose Effective For Treatment Of Bipolar Disorder And Adjust To Lowest Effective Dose; Usual Dose 300-800 Mg Once Daily
Adjunctive Treatment Of Major Depression:
Extended-Release Tab:
- Adult: 50 Mg Once Daily For 2 Days, Dose To Be Taken At Bedtime, Then 150 Mg Once Daily For 2 Days, Then, Adjusted According To Response, Usual Dose 150-300 Mg Once Daily
- Elderly: Initially 50 Mg Once Daily For 3 Days, Then Increased If Necessary To 100 Mg Once Daily For 4 Days, Then Adjusted In Steps Of 50 Mg, Adjusted According To Response, Usual Dose 50-300 Mg Once Daily, Dose Of 300mg Should Not Be Reached Before Day 22 Of Treatment
Content
- Tab 25mg /100mg /150mg /200mg /300mg /400mg: Quetiapine Fumarate Equiv To Quetiapine 25mg /100mg /150mg /200mg /300mg /400mg.
- Tab Extended Release 50mg /200mg /300mg /400mg: Quetiapine Fumarate Equiv To Quetiapine 50mg /200mg /300mg /400mg.
Pregnancy
Avoid Unless Potential Benefit Outweighs Risk
Stability
Contra Indications
Precautions
Lactation
Side Effects
- Asthenia
- Dysarthria
- Dyspnea
- Elevated Plasma-cholesterol And Plasma-triglyceride Concentrations
- Increased Appetite
- Irritability
- Peripheral Oedema
- Sleep Disorders
- Hyponatraemia
- Hypothyroidism
- Restless Legs Syndrome
- Rhinitis
- Suicidal Behaviour (particularly On Initiation)
- Toxic Epidermal Necrolysis.
- Rare: Angioedema
- Hepatitis
- Pancreatitis
- Inappropriate Secretion Of Antidiuretic Hormone
- Rhabdomyolysis
- Stevens-johnson Syndrome