Vitamin B1, also known as thiamine, is a vital nutrient that helps the body convert food into energy. It is an important coenzyme in many metabolic processes, including those that support healthy nerve and muscle function. When used therapeutically, vitamin B1 and combinations of B1, B6, and B12 are often prescribed to treat various neurological and cardiovascular conditions. These supplements have been shown to improve symptoms of peripheral neuropathy, diabetic neuropathy, and other nerve-related disorders.