Alfacalcidol

Therapeutic Group

Vitamin A, D & Combinations

Indication Dosage

Severe Renal Impairment Requiring Vitamin D Therapy: 

Oral Or By IV Inj: 

  • Adult: Initially 1 Microgram Daily, Oral Or IV Injection Over 30 Sec, Adjusted Dose To Avoid Hypercalcaemia; Maintenance 0.25-1 Microgram Daily. 
  • Elderly: Initially 500 Nanograms Daily, Adjusted Dose To Avoid Hypercalcaemia; Maintenance 0.25-1 Microgramdaily 

Hypophosphataemic Rickets, Persistent Hypocalcemia due To Hypoparathyroidism Or Pseudohypoparathyroidism: 

Oral Or By IV Inj: 

  • Children 1 Month-11 Yrs: 25-50 Nanograms/kg Oral Or IV Injection Over 30 Sec, Once Daily; Maximum1 Microgram Per Day. 
  • Children 12 & Above: 1 Microgram Once Daily, Oral Or IV Injection Over 30 Sec. 

Prevention Of Vitamin D Deficiency In Renal Or Cholestatic Liver Disease: 

Oral Or By IV Inj: 

  • Children 1 Month-11 Yrs:(body weight Up To 20 Kg):15-30 Nanograms/kg Once Daily; Max. Per Dose 500nanograms; (body weight 20 Kg And above): 250-500 Nanograms Once Daily, Oral Or IV Injection Over 30 Sec 
  • Children 12yrs & Above: 250-500 Nanograms Once Daily. One Drop Of Alfacalcidol 2 Microgram/ml Oral Drops Contains Approximately 100 Nanograms of Alfacalcidol, Oral Or IV Injection Over 30 Sec

Content

  • Cap /Tab 0.25 Mcg /0.5 Mcg /1 Mcg: Alfacalcidol 0.25 Mcg /0.5 Mcg /1 Mcg.
  • Drop Per ml: Alfacalcidol 0.2 Mcg.
  • Inj 1 Mcg: Per 0.5 ml: Alfacalcidol 1 Mcg.

Pregnancy

Risk Cannot Be Ruled Out.

Stability

  • Vitamin D Analogue

Contra Indications

  • Hypercalcaemia, Metastatic Calcification.

Precautions

  • Hypercalcaemia, Metastatic Calcification.

Lactation

  • Caution Advised

Side Effects

  • Rare: Nephrocalcinosis
  • Pruritus
  • Rash
  • Urticaria
  • Symptoms Of Overdose Include Anorexia
  • Lassitude
  • Weight Loss
  • Gi Disorders
  • Polyuria
  • Sweating
  • Headache
  • Thirst
  • Vertigo And Raised Concentration Of Calcium And Phosphate In Plasma And Urine.

Available Brands