Amitriptyline

Therapeutic Group

Anti-depressants

Indication Dosage

Amitriptyline is a medication that is commonly used to treat conditions like depression and certain types of chronic pain. It helps improve mood and can reduce persistent pain, making it easier for people to feel better and live more comfortably. Your doctor may prescribe amitriptyline if they believe it can help with your specific symptoms and needs. Always follow your doctor's instructions when taking this medication.

Depressive Illness: 

  • Adult & Children Above 16 Yrs: Initially 75 Mg Daily In Divided Doses, Alternatively Initially 75 Mg Once Daily At Bedtime, Increased If Necessary To 150-200 Mg Daily, Increased Gradually 
  • Elderly: Initially 30-75 Mg Daily In Divided Doses, Alternatively Initially 30-75 Mg Once Daily At Bedtime, Increased If Necessary To 150-200 Mg Daily, Increased Gradually 

Neuropathic Pain: 

  • Adult & Children Above 16 Yrs: Initially 10 Mg Once Daily, Increased If Necessary To 75 Mg Once Daily, Dose To Be Taken At Night, Increased Gradually 

Migraine Prophylaxis: 

  • Adult: Initially 10 Mg Once Daily, Then Increased If Necessary To 50-75 Mg Once Daily At Night (max. Per Dose 150 Mg)

Content

  • Tab 10mg /25mg: Amitriptyline Hci 10mg /25mg.
  • Cap 25mg /50mg: Amitriptyline Hci 25mg /50mg.

Pregnancy

Avoid Unless Potential Benefit Outweighs Risk

Stability

  • Tricyclic Antidepressant

Contra Indications

  • Arrhythmias, Acute Porphyrias, During Manic Phase Of Bipolar Disorder, Heart Block, Immediate Recovery Period After Myocardial Infarction, Severe Liver Disorder

Precautions

  • Arrhythmias, Acute Porphyrias, During Manic Phase Of Bipolar Disorder, Heart Block, Immediate Recovery Period After Myocardial Infarction, Severe Liver Disorder

Lactation

  • Contraindicated, Avoid

Side Effects

  • Agitation
  • Anorexia
  • Fatigue
  • Hypertension
  • Mydriasis
  • Oedema
  • Palpitation
  • Restlessness
  • Stomatitis
  • Blurred Vision
  • Confusion
  • Constipation
  • Convulsions
  • Delusions
  • Dizziness
  • Drowsiness
  • Dry Mouth
  • Ecg Changes
  • Gynaecomastia
  • Haematological Reactions
  • Hallucinations
  • Headache
  • Heart Block
  • Hepatic Reactions
  • Hypomania
  • Hyponatraemia
  • Increased Intra-ocular Pressure
  • Irritability
  • Mania
  • Movement Disorders
  • Myalgia
  • Paraesthesia
  • Photosensitivity
  • Postural Hypotension
  • Pruritus
  • Rash
  • Sexual Dysfunction
  • Sleep Disturbances
  • Suicidal Behavior
  • Sweating
  • Tachycardia
  • Tinnitus
  • Urinary Retention
  • Urticaria
  • Vomiting
  • Weight Changes.
  • Rare: Alopecia
  • Arrhythmia
  • Dysarthria
  • Extrapyramidal Symptoms
  • Paralytic Ileus
  • Tremor