Amoxicillin And Flucloxaclilin

Therapeutic Group

Beta-Lactam Anti-bacterials, Penicillins

Indication Dosage

Mixed-infections Involving Beta-lactamase-producing Staphylococci: 

Oral: 

  • Adults: 500 Mg (amoxicillin 250 Mg & Flucloxacillin 250 Mg) Every 6 Hr, Dose Doubled In Severe Infections. 
  • Children Above 10 Yr: Adult Dose; Below 10 Yr: Half Adult Dose, The Dose Doubled In Severe Cases. 

By IV Or IM Inj: 

  • Adults: 500 Mg (amoxicillin 250 Mg & Flucloxacillin 250 Mg) Every 6 Hr, Dose Doubled In Severe Infections. 
  • Children 2-10 Yrs: Half Adult Dose, The Dose Doubled In Severe Cases.

Content

  • Cap 500mg: Amoxicillin 250mg, Flucloxacillin 250mg.
  • Inj: 500mg: Amoxicillin 250mg, Flucloxacillin 250mg; Powder In Vial.
  • Susp: 250mg: Per 5 ml: Amoxicillin 125mg, Flucloxacillin125mg

Pregnancy

Not Known To Be Harmful

Stability

  • Broad-spectrum Peniciltin
  • Penicillinase-resistant Penicillin

Contra Indications

  • History Of Flucloxacillin Associated Jaundice/hepatic Dysfunction, Hypersensitivity To Penicillins, Cephalosporins Or Other Beta-lactams.

Precautions

  • History Of Flucloxacillin Associated Jaundice/hepatic Dysfunction, Hypersensitivity To Penicillins, Cephalosporins Or Other Beta-lactams.

Lactation

  • Not Known to Be Harmful

Side Effects

  • Hypersensitivity Reaction
  • Gi Disturbance
  • Nausea And Vomiting.
  • Rare: Hepatitis
  • Cholestatic Jaundice
  • Haematological And Cns Effects
  • Pseudomembranous Colitis
  • Increased Inr
  • Stevens-johnson's Syndrome
  • Toxic Epidermal Necrosis.

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