Anastrozole

Therapeutic Group

Endocrine Hormone Therapy

Indication Dosage

Anastrozole is a medication primarily prescribed for the treatment of postmenopausal women with hormone receptor-positive breast cancer. It belongs to a class of drugs known as aromatase inhibitors and is used to inhibit the production of estrogen, a hormone that can promote the growth of certain types of breast tumors. Anastrozole is employed as an adjuvant therapy following surgery or radiation therapy to reduce the risk of cancer recurrence and as a first-line treatment in advanced breast cancer cases. It plays a crucial role in helping to manage and control the progression of hormone-sensitive breast cancer in postmenopausal women.

Adjuvant Treatment Of Oestrogen-receptor-positive Early Invasive Breast Cancer In Postmenopausal Women Or Following 2-3 Years Of Tamoxifen Therapy Or Advanced Breast Cancer In Postmenopausal Women Which Is Oestrogen-receptor Positive Or Responsive To Tamoxifen: 

  • Adult: 1 Mg Daily. 
  • Children: Not Recommended.

Content

  • Tab: Anastrozole1mg.

Pregnancy

Positive Evidence Of Risk: Avoid

Stability

  • Aromatase Inhibitor

Contra Indications

  • Pre-menopausal Women, Moderate To Severe Hepatic Impairment, Severe Renal Impairment; Avoid If Creatinine Clearance Less Than 20 Ml/minute,

Precautions

  • Pre-menopausal Women, Moderate To Severe Hepatic Impairment, Severe Renal Impairment; Avoid If Creatinine Clearance Less Than 20 Ml/minute,

Lactation

  • Avoid. Discontinue Breast-feeding.

Side Effects

  • Allergic Reactions
  • Anaphylaxis
  • Angioedema
  • Anorexia
  • Arthralgia
  • Arthritis
  • Asthenia
  • Bone Fractures
  • Bone Pain
  • Cutaneous Vasculitis
  • Diarrhoea
  • Drowsiness
  • Hair Thinning
  • Headache
  • Hot Flushes
  • Nausea
  • Rash
  • Slight Increases In Total Cholesterol Levels
  • Stevens-johnson Syndrome
  • Vaginal Bleeding
  • Vaginal Dryness
  • Vomiting.

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