Vinorelbine Sulfate

Therapeutic Group

Anti-neoplastics

Indication Dosage

Vinorelbine sulfate is a medication primarily indicated for the treatment of advanced non-small cell lung cancer (NSCLC) and metastatic breast cancer. It is commonly used when other treatments have not been effective or as a part of combination therapy regimens. Vinorelbine sulfate works by inhibiting the growth and spread of cancer cells, offering hope to patients facing these challenging diagnoses.

First Line Treatment Of Stage Iii Or IV non-small Cell Lung Cancer Alone Or In Combination, Treatment Of Stage 3 Or 4 Advanced Breast Cancer Relapsing Or Refractory To Anthracycline-Containing Regimens: 

By IV Inj: 

  • Adults & Elderly: Monotherapy: 30 Mg/m2 Every 7 Day. Combination Therapy With Cisplatin: 25 Mg/m2 Every 7 Day (with Cisplatin100 Mg/m2 Every 4 Week). Alternatively: 30 Mg/m2 In Combination With Cisplatin 120 Mg/m2 On Days 1 & 29, Then Every 6 Wk.

Content

  • Inj 10mg /50mg: Per ml: Vinorelbine 10mg; 1 ml And 5 ml Solution.

Pregnancy

Contraindicated.

Stability

  • Vinca Alkaloid

Contra Indications

  • Myelosuppression.

Precautions

  • Myelosuppression.

Lactation

  • Contraindicated. Discontinue Breast-feeding

Side Effects

  • Alopecia
  • Autonomic Neuropathy
  • Bone Marrow Suppression
  • Extravasation
  • Hyperuricaemia
  • Irritant To Tissues
  • Myelosuppression
  • Neurotoxicity
  • Oral Mucositis
  • Peripheral Neuropathy
  • Severe Bronchospasm
  • Severe Local Irritation
  • Thromboembolism
  • Tumourlysis Syndrome
  • Vomiting