Atracurium Besylate

Therapeutic Group

Muscle Relaxant

Indication Dosage

Neuromuscular Blockade (short To Intermediate Duration) For Surgery And Wide Range Of Procedures, To Facilitate Controlled Ventilation And Endotracheal Intubation: 

By IV Inj: 

  • Adult: Initially 300-600 Mcg/kg, Then (by IV Injection) 100-200 Mcg/kg As Required, This Dosage Provides Relaxation For 15-35 Min. Full Block Can Be Prolonged With Supplementary Doses Of 0.1-0.2 Mg/kg As Required. Endotracheal Intubation Can Usually Be Accomplished Within 90 Sec From The IV Inj Of 0.5-0.6 Mg/kg. As An Infusion: After An Initial Bolus Dose Of 0.3-0.6 Mg/kg Neuromuscular Block Can Be Maintained By Administration As A Continuous Infusion At Rates Of 0.3-0.6, Mg/kg/hr 
  • Children Neonate: Initially By IV Injection 300-500 Mcg/kg Followed Either By IV Injection, 100-200 Mcg/kg Repeated As Necessary Or By IV Infusion, 300-400 Mcg/kg/hr Adjusted According To Response 
  • 1 Month-18 Yr: Initially By IV Injection 300-600 Mcg/kg Then 100-200 Mcg /kg Repeated As Necessary Or Initially By IV Injection 300-600 Mcg/kg Followed By IV Infusion, 300-600 Mcg/kg/hr Adjusted According To Response. 

Neuromuscular Blockade During Intensive Care: 

By IV Inj: 

  • Adult: Initially 300-600 Mc/kg, Initial Dose Is Optional, Then (by Intravenous Infusion) 270-1770 Mc/kg/hour; (by Intravenous Infusion) Usual Dose 650-780 Mcg/kg/hour 
  • Children Neonate: Initially By IV Injection 300-500 Mcg/kg Followed Either By IV Injection, 100-200 Mcg /kg Repeated As Necessary Or By IV Infusion, 300-400 Mcg/kg/hr Adjusted According To Response; Higher Doses May Be Necessary.
  • 1 Month-18 Yr: Initially By IV Injection 300-600 Mcg/kg (optional) Then By IV Infusion, 270-1770 Mcg/kg/hr (usual Dose 650-780 Mcg/kg/ Hr).

Content

  • Inj: Per ml: Atracurium Besylate 10mg.

Pregnancy

Caution Advised

Stability

  • Non-depolarising Neuromuscular Blocking Drugs

Contra Indications

  • Atracurium Besylate Hypersensitivity.

Precautions

  • Atracurium Besylate Hypersensitivity.

Lactation

  • Caution Advised

Side Effects

  • Anaphylactoid Reactions (rare)
  • Acute Myopathy (after Prolonged Use In Intensive Care)
  • Bronchospasm
  • Hypotension
  • Seizures
  • Skin Flushing
  • Tachycardia
  • Cardiovascular Effects