Bendamustine Hcl

Therapeutic Group

Anti-neoplastics

Indication Dosage

Bendamustine HCl is a medication used to treat certain types of cancer, particularly non-Hodgkin lymphoma and chronic lymphocytic leukemia (CLL). It works by slowing down or stopping the growth of cancer cells in the body. Your doctor may prescribe Bendamustine HCl when other treatments have not been effective or as a part of your cancer treatment plan.

Chronic Lymphocytic Leukemia (CLL): 

By IV Infusion: 

  • Adult: 100 Mg/m2 Administered Intravenously Over 30 Minutes On Days 1 And 2 Of A 28-day Cycle, Up To 6 Cycles 

Non-Hodgkin's Lymphoma (NHL): 

By IV Infusion: 

  • Adult: 120 Mg/m2 Administered Intravenously Over 60 Minutes On Days 1 And 2 Of A 21-day Cycle, Up To 8 Cycles.

Content

  • Inj 100mg: Bendamustine Hcl 100mg As Lyophilized Powder

Pregnancy

Positive Evidence Of Harm: Avoid

Stability

  • Antineoplastic, Nitrogen Mustard Analogues

Contra Indications

  • Anaphylactic And Anaphylactoid Reactions To The Drug

Precautions

  • Anaphylactic And Anaphylactoid Reactions To The Drug

Lactation

  • Contraindicated. Discontinue Breast-feeding

Side Effects

  • Abdominal Pain And Distension
  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Stomatitis
  • Dyspepsia
  • Gi Reflux Disease
  • Fatigue
  • Pyrexia
  • Chills
  • Edema Peripheral
  • Asthenia
  • Chest Pain
  • Tachycardia
  • Herpes Zoster
  • Upper Respiratory Tract Infection
  • Urinary Tract Infection
  • Sinusitis
  • Pneumonia
  • Febrile Neutropenia
  • Oral Candidiasis
  • Nasopharyngitis
  • Anorexia
  • Decreased Appetite
  • Hypokalemia
  • Back Pain
  • Arthralgia
  • Pain In Extremity
  • Headache
  • Dizziness
  • Dysgeusia
  • Insomnia
  • Anxiety
  • Depression
  • Cough
  • Dyspnea
  • Pharyngolaryngeal Pain
  • Wheezing
  • Nasal Congestion
  • skin Rash
  • Pruritus
  • Hyperhidrosis
  • Hypotension. Decreased Hemoglobin
  • Platelets
  • Leukocytes
  • Lymphocytes And Neutrophils.

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