Atezolizumab

Therapeutic Group

Anti-neoplastics

Indication Dosage

Atezolizumab is a medication used to treat certain types of cancer. It helps your immune system fight cancer cells, and it's often prescribed when other treatments haven't worked. Your doctor may recommend Atezolizumab for your specific type of cancer to help improve your chances of recovery.

As Monotherapy; For The Treatment Of Patients With Locally Advanced Or Metastatic Urothelial Carcinoma (UC), For The Treatment Of Adult Patients With Locally Advanced Or Metastatic Non-small Cell Lung Cancer (NSCLC) After Prior Chemotherapy: 

By IV Infusion: 

  • Adults: The Recommended Dose Is 1,200 Mg Administered Intravenously Every Three Weeks. Consult Product Literature 

In Combination With Bevacizumab, Paclitaxel, And Carboplatin, For The First-line Treatment Of Adult Patients With Metastatic Non-squamous Non-small Cell Lung Cancer (NSCLC). In Patients With Egfr Mutant Or Alk-positive Nsclc, Only After Failure Of Appropriate Targeted Therapies: 

By IV Infusion: 

  • Adults: Consult Product Literature And Refer To The Full Prescribing Information For The Combination Therapy

Content

  • Inj 1200mg /20ml: Pertuzumab 30mg /ml Solution For Infusion Single Use Vial

Pregnancy

Positive Evidence Of Risk: Avoid

Stability

  • Recombinant Humanized Monoclonal Antibody

Contra Indications

  • None Known

Precautions

  • None Known

Lactation

  • Contraindicated. Discontinue Breast-feeding

Side Effects

  • Anaemia
  • Cardiovascular Disorder
  • Thrombocytopenia
  • Neutropenia
  • Thrombocytopenia
  • Hypothyroidism
  • Hyperthyroidism
  • Diabetes Mellitus
  • Adrenal Insufficiency
  • Urinary Tract Infections
  • Decreased Appetite
  • Hypomagnesaemia
  • Hypokalaemia
  • Hyponatremia
  • Peripheral Neuropathy
  • Guillain-Barre syndrome
  • Meningoencephalitis
  • Hypotension
  • Cough
  • Dyspnoea
  • Pneumonitis
  • Hypoxia
  • Nasal Congestion
  • Nausea
  • Vomiting
  • Diarrhoea
  • Constipation
  • Abdominal Pain
  • Colitis
  • Dysphagia
  • Stomatitis
  • Pancreatitis
  • Ast Increased
  • Alt Increased
  • Hepatitis
  • Rash
  • Pruritus
  • Arthralgia
  • Musculoskeletal Pain
  • Pyrexia
  • Fatigue
  • Asthenia
  • Infusion-related Reactions
  • Influenza Like Illness
  • Chills.
  • Rare: Hypophysitis
  • Myasthenic Syndrome
  • Myocarditis
  • Nephritis

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