Benzathine Penicillin G

Therapeutic Group

Beta-Lactamase Sensitive Penicillins

Indication Dosage

Mild To Severe Streptococcal Infections Group A Of Upper Respiratory Tract, Skin And Soft Tissues, Scarlet Fever, Erysipelas, Otitis Media: 

By Deep IM Inj: 

  • Adults: 2.4 Million Units. 
  • Children: 30-60 Lbs, 0.9-1.2 Million Units; Infants & Children Under 30 Lbs., 0.6 Million Units, Injection At A Single Session Using Multiple Im Sites When Indicated. Alternatively, Give 1/2 The Total Dose On Day 1 And the Remaining 1/2 Of the Total Dose On Day 3. 

Pneumococcal Infections (except Pneumococcal Meningitis): 

By Deep IM Inj: 

  • Adults: 1.2 Million Units. 
  • Children: 0.6 Million Units, Repeated Every 2 Or 3 Days Until The Temperature Is Normal For 48 Hr

Content

  • Inj 0.6 Miu: Benzathine Penicillin G 0.6 Miu (long Acting), Vial.
  • Inj 1.2 Miu: Benzathine Penicillin G 1.2 Miu (long Acting), Vial.inj 2 Benzathine Penicillin G 2.4 Miu (long Acting), Vial

Pregnancy

No Evidence Of Harm

Stability

  • Beta Lactamase Sensitive Penicillin

Contra Indications

  • History Of Previous Hypersensitivity Reaction To Penicillins And/or Cephalosporins.

Precautions

  • History Of Previous Hypersensitivity Reaction To Penicillins And/or Cephalosporins.

Lactation

  • Caution Advised

Side Effects

  • Gi Disturbances
  • Anaemias
  • Anaphylaxis
  • Glossitis
  • Stomatitis
  • Gastritis
  • Sore Throat
  • Dry Mouth
  • Furry Tongue
  • Hemorrhagic Manifestation
  • Interstitial Nephritis (e.g Oliguria
  • Hematuria)
  • Nephrotoxicity
  • Accumulation Of Sodium From Injection Can Occur In Renal Failure. High Doses May Cause Neurotoxicity
  • Including Cerebral Irritation
  • Convulsions
  • Or Coma.

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