Ticarcillin And Clavulanic Acid

Therapeutic Group

Beta-Lactam Anti-bacterials, Penicillins

Indication Dosage

Infections Due To Pseudomonas And Proteus Species: 

By IV Infusion: 

  • Adult: 3.2 G Every 6-8 Hours; Increased If Necessary To3.2 G Every 4 Hours, For More Severe Infections 
  • Children: 80 Mg/kg Six To Eight Hourly; Neonates, 80 Mg/kg 12 Hourly, 
    Children Above 40 Kg Same As Adult Dose. 

Septicaemia, Bone Infection: 

By IV Infusion: 

  • Adults: 200-300 Mg/kg/day Ticarcillin Given Every 4-6 Hr. 
  • Children 3 Month Less Than 60 Kg Body Weight: 50 Mg/kg/day Ticarcillin Given Every 4 Hr; Above 60 Kg Body Weight: 3.2 Gm Every 4-6 Hr.

Content

  • Infusion 3.2gm: Clavulanic Acid 200mg (as Potassium Salt), Ticarcillin 3gm (as Sodium Salt); Powder For Infusion Vial

Pregnancy

No Evidence Of Harm

Stability

  • Beta-lactamase Inhibitor
  • Broad-spectrum Penicillin

Contra Indications

  • Hypersensitivity To Penicillins, Cephalosporins Or Other Beta-lactams.

Precautions

  • Hypersensitivity To Penicillins, Cephalosporins Or Other Beta-lactams.

Lactation

  • Caution Advised

Side Effects

  • Gi Disturbances
  • Nausea
  • Vomiting
  • Constipation
  • Dyspepsia
  • Headache
  • Hypersensitivity
  • Gi Upset. Rarely
  • Hepatitis
  • Cholestatic Jaundice
  • Haematological And Cns Effects
  • Hypokalaemia
  • Pseudomembranous Colitis

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