Bisoprolol And Hydrochlorothiazide

Therapeutic Group

Beta Blocking Agent

Indication Dosage

Hypertension, Angina: 

  • Adults: 1 Tab Once Daily, Max; Bisoprolol 20 Mg And Hydrochlorothiazide 12.5 Mg. 
  • Children: Not Recommended.

Content

  • Tab 5 /6.25mg: Bisoprolol (as Fumarate) 5 Nig, Hy-drochlorothiazide 6.25mg.
  • Tab 10 /6.25mg: Bisoprolol (as Fumarate) 10mg, Hydrochlorothiazide 6.25mg.
  • Tab 5 /12.5mg: Bisoprolol (as Fumarate) 5mg, Hydrochlorothiazide 12.5mg.

Pregnancy

Avoid, Risk Cannot Be Ruled Out.

Stability

  • Beta-blocker
  • Diuretic

Contra Indications

  • Acute Or Decompensated Heart Failure Requiring Intravenous Inotropes, Sino-atrial Block, 2nd Or 3rd Degree Av Block (without Pacemaker), Severe Bradycardia, Uncontrolled Heart Failure, Cardiogenic Shock, Severe Peripheral Arterial Disease, Hypotension, Metabolic Acidosis, Untreated Pheochromocytoma, Severe Asthma Or Copd.

Precautions

  • Acute Or Decompensated Heart Failure Requiring Intravenous Inotropes, Sino-atrial Block, 2nd Or 3rd Degree Av Block (without Pacemaker), Severe Bradycardia, Uncontrolled Heart Failure, Cardiogenic Shock, Severe Peripheral Arterial Disease, Hypotension, Metabolic Acidosis, Untreated Pheochromocytoma, Severe Asthma Or Copd.

Lactation

  • Contraindicated or Not Recommended.

Side Effects

  • Cardiovascular Effects Including Bradycardia
  • Postural Hypotension
  • Increased Av Block
  • Cardiac Arrhythmias
  • Raynaud's Phenomenon
  • Cold Extremities
  • Sexual Dysfunction
  • Gi Upset
  • Sleep And Cns Disturbances
  • Skin Reactions
  • Fatigue
  • Paraesthesia
  • Peripheral Neuropathy
  • Arthralgia
  • Myopathy
  • Altered Blood Sugar Haematology And Lipid Levels. Withdraw If Unexplained Dry Eyes Or Rash. Rarely
  • Heart Failure
  • Dyspnea
  • Bronchospasm

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