Bisoprolol Fumarate

Therapeutic Group

Beta Blocking Agent

Indication Dosage

Hypertension, Angina: 

  • Adult: 5-10 Mg Tab Once Daily; Maximum 20 Mg Per Day 

Adjunct In Heart Failure: 

  • Adult: Initially 1.25 Mg Tab Once Daily For 1 Week, Dose To Be Taken In The Morning, Then Increased If Tolerated To 2.5 Mg Once Daily For 1 Week, Then Increased To 3.75 Mg Once Daily For 1 Week, Then Increased To 5 Mg Once Daily For 4 Weeks, Then Increased To 7.5 Mg Once Daily For4 Weeks, Then Increased To 10 Mg Once Daily; Max 10 Mg Per Day 
  • Children: Not Recommended.

Content

  • Tab 2.5mg /5mg /10mg: Bisoprolol Fumarate 2.5mg /5mg /10mg.

Pregnancy

Avoid, Risk Cannot Be Ruled Out.

Stability

  • Beta-blocker

Contra Indications

  • Acute Or Decompensated Heart Failure Requiring Intravenous Inotropes, Sino-atrial Block, 2nd Or 3rd Degree Av Block (without Pacemaker), Severe Bradycardia, Uncontrolled Heart Failure, Cardiogenic Shock, Severe Peripheral Arterial Disease, Hypotension, Metabolic Acidosis, Untreated Pheochromocytoma, Severe Asthma Or Copd.

Precautions

  • Acute Or Decompensated Heart Failure Requiring Intravenous Inotropes, Sino-atrial Block, 2nd Or 3rd Degree Av Block (without Pacemaker), Severe Bradycardia, Uncontrolled Heart Failure, Cardiogenic Shock, Severe Peripheral Arterial Disease, Hypotension, Metabolic Acidosis, Untreated Pheochromocytoma, Severe Asthma Or Copd.

Lactation

  • Caution Advised

Side Effects

  • Cardiovascular Effects Including Bradycardia
  • Postural Hypotension
  • Increased Av Block
  • Cardiac Arrhythmias
  • Raynaud's Phenomenon
  • Cold Extremities
  • Sexual Dysfunction
  • Gi Upset
  • Sleep And Cns Disturbances
  • Skin Reactions
  • Fatigue
  • Paraesthesia
  • Peripheral Neuropathy
  • Arthralgia
  • Myopathy
  • Altered Blood Sugar Haematology And Lipid Levels. Withdraw If Unexplained Dry Eyes Or Rash.
  • Rare: Heart Failure
  • Dyspnea
  • Bronchospasm

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