Cefotaxime
Therapeutic Group
Other Beta-Lactam, Cephalosporins & PenemsIndication Dosage
Infections Due To Sensitive Gram-positive And Gram-negative Bacteria, Surgical Prophylaxis, Haemophilus Epiglottitis:
By IM Inj, OrIV Inj, Or Iv Infusion:
- Adult: 1 G Every 12 Hours
- Children: 100-150 Mg/kg Daily; Neonates, 50 Mg/kg Daily, In Two To Four Divided Doses; Max 200 Mg/kg Daily
Severe Infections Due To Sensitive Gram-positive And Gram-negative Bacteria, Septicaemia, Meningitis:
By IM Inj, OrIV Inj, Oriv Infusion:
- Adult: 8 G Daily In 4 Divided Doses, Increased If necessary To 12 G Daily In 3-4 Divided Doses. Im Doses Over 1 G Should Be Divided between More Than One Site
By IV Inj:
- Children: 0-1 Week: 50 Mg/kg Every 12 Hr; 1-4 Weeks: 50 Mg/kg Every 8 Hr;
- 1 Month-12 Yr: Less Than 50 Kg Body Weight: 50-180 Mg/kg/day Divided Into 4-6 Doses.
Emergency Treatment Of Suspected Bacterial Meningitis Or Meningococcal Disease, Before Urgent Transfer To Hospital:
By Iv Or IM Inj:
- Adult & Children Above 12 Years: 1 G For 1 Dose
- Children 1 Month-11 Years: 50 Mg/kg For 1 Dose
Uncomplicated Gonorrhoea
By IM Inj:
- Adult: 500 Mg For 1 Dose
Bone & Joints Infection:
By IM Inj, Or IV Inj:
- Adults & Children: Above 50 Kg Body Weight: 1-2 Gm Every 8 Hr. Max: 12 Gm/day.
By IV Inj:
- Children: 0-1 Week: 50 Mg/kg Every 12 Hr; 1-4 Weeks: 50 Mg/kg Every 8 Hr;
- 1 Month-12 Yr: Less Than 50 Kg Body Weight: 50-180 Mg/kg/day Divided Into 4-6 Doses.
Content
- Inj 250mg /500mg /1gm /2gm: Cefotaxime Sodium Equiv To 250mg /500mg /1gm /2gmcefotaxime; Powder In Vial.
Pregnancy
No Evidence Of Harm
Stability
- Antibacterials
- Cephalosporins
Contra Indications
- None Known
Precautions
- None Known
Lactation
- Caution Advised
Side Effects
- Abdominal Discomfort
- Agranulocytosis
- allergic Reactions
- anaphylaxis
- Aplastic Anaemia
- Blood Disorders
- Confusion
- Disturbances In Liver Enzymes
- Dizziness
- Eosinophilia
- Haemolytic Anaemia
- Headache
- Hypertonia
- Leucopenia
- Nervousness
- Pruritus
- Rashes
- Fever And Arthralgia
- Sleep Disturbances
- Urticaria
- Gi Disturbances
- Rare: Stevens-johnsonsyndrome
- Thrombocytopenia
- Toxic Epidermal Necrolysis
- Transient Cholestatic Jaundice
- Transient Hepatitis
Available Brands
- 1. Adwotex
- 2. Afran
- 3. Albaxim
- 4. Algixim
- 5. Alsef
- 6. Astetaxm
- 7. Avetek
- 8. Awabrod
- 9. Axotroxen
- 10. Bacxime
- 11. Baxim
- 12. Biolog
- 13. Biotaxime
- 14. Bioxim
- 15. Boscef
- 16. Breetex
- 17. Cafran
- 18. Cefabest
- 19. Cefdox
- 20. Cefnixa
- 21. Cefoc
- 22. Cefomed
- 23. Cefomerc
- 24. Cefon
- 25. Cefora
- 26. Cefotam
- 27. Cefotax
- 28. Cefoxim
- 29. Ceftax
- 30. Cefti
- 31. Ceftifixe
- 32. Ceftisav
- 33. Ceftop
- 34. Ceftoringe
- 35. Cefwise
- 36. Cephronate
- 37. Claforan
- 38. Clafort
- 39. Claftax
- 40. Clagen Show More