Cefoperazone And Sulbactam

Therapeutic Group

Other Beta-Lactam, Cephalosporins & Penems

Indication Dosage

Infection Of the Respiratory Tract, Urinary Tract, Skin and Soft Tissue, Bone and joint, And Intra-abdominal Infections, Peritonitis, Cholecystitis, Septicaemia, and Meningitis:

By IV Inj:

Adults: 2-4 Gm A Day In Equally Divided Doses Every 12 Hr, May Be Increased Up To Max 8 Gm A Day (equivalent To Cefoperazone 4 Gm A Day) In Severe Infections.
Children: 40-80 Mg/kg/day In 2-4 Equally Divided Doses, May Be Increased Up To Max 180 Mg/kg/day In Severe Infections. Newborn Infants To 1 Week: 40-80 Mg/kg/day Every 12 Hr. Max Sulbactam Dose In Children 80 Mg/kg/day. For Cefoperazone Dose Higher Than 80 Mg/kg/day, Given Cefoperazone Separately.

Content

Inj 500mg: Sulbactam 250mg, CefoPerazone 250mg; Powder In Vial.inj 1gm: Sulbactam 500mg, CefoPerazone 500mg; Powder In Vial.
Inj 2gm: Sulbactam 1000mg, CefoPerazone 1000mg; Powder In

Pregnancy

Caution Advised

Stability

Beta-lactamase Inhibitor
Cephalosporin

Contra Indications

History Of Allergies To Penicillins, Cephalosporins Or Sulbactam.

Precautions

History Of Allergies To Penicillins, Cephalosporins Or Sulbactam.

Lactation

Caution Advised

Side Effects

Abdominal Discomfort
Agranulocytosis
Allergic Reactions
Anaphylaxis
Aplastic Anaemia
Blood Disorders
Confusion
Disturbances In Liver Enzymes
Dizziness
Eosinophilia
Haemolytic Anaemia
Headache
Hypertonia
Leucopenia
Nervousness
Pruritus
Rashes
Fever And Arthralgia
Sleep Disturbances
Urticaria
Gi Disturbances
Rare: Stevens-johnson Syndrome
Thrombocytopenia
Toxic Epidermal Necrolysis
Transient Cholestatic Jaundice
Transient Hepatitis