Cefoperazone

Therapeutic Group

Other Beta-Lactam, Cephalosporins & Penems

Indication Dosage

Severe Infections Of Gram-negative Or From Mixed Flora In The Presence Of Gram-negative Bacteria, Resistant To Other Antibiotics: 

By IM Or IV Inj: 

  • Adults: 1-2 Gm Twice Daily, Adult Dose May Be Doubled If Administered By IV. Max 9 Gm Daily In Divided Doses. 
  • Children & Infants: 50-200 Mg/kg/day Given In Two Or More Administrations. For Neonates (less Than 8 Days), The Drug Should Be Given Every 12 Hr.

Content

  • Inj 0.25gm /0.5gm /1gm /2gm: CefoPerazone0.25gm /0.5gm /1gm /2gm (as Sodium); Powder In Vial And Ampoule Containing Solvent.

Pregnancy

Caution Advised

Stability

  • Cephalosporin Antibiotics

Contra Indications

  • None Known

Precautions

  • None Known

Lactation

  • Caution Advised

Side Effects

  • Abdominal Discomfort
  • Agranulocytosis
  • Allergic Reactions
  • Anaphylaxis
  • Aplastic Anaemia
  • Blood Disorders
  • Confusion
  • Disturbances In Liver Enzymes
  • Dizziness
  • Eosinophilia
  • Haemolytic Anaemia
  • Headache
  • Hypertonia
  • Leucopenia
  • Nervousness
  • Pruritus
  • Rashes
  • Fever And Arthralgia
  • Sleep Disturbances
  • Urticaria
  • Gi Disturbances.
  • Rare: Stevens-johnson Syndrome
  • Thrombocytopenia
  • Toxic Epidermal Necrolysis
  • Transient Cholestatic Jaundice
  • Transient Hepatitis

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