Colistimethate Sodium

Therapeutic Group

Other Anti-Bacterial

Indication Dosage

Gram-negative Infections Resistant To Other Antibacterials, Including Those Caused By Pseudomonas Aeruginosa, Acinetobacter baumanii And Klebsiella Pneumonia: 

By Slow IV Injection, Or By IV Infusion: 

  • Adult (body weight Up To 60 Kg): 50,000-75,000 Units/kg Daily In 3 Divided Doses Every 8 Hrs. 
  • Adult (body weight 60 Kg And Above): 1-2 Million Units Every 8 Hrs, Max 6 Million Units Per Day

Content

  • Inj: Per Vial: Colistimethate Sodium (colistin Sulfomethate Sodium) 80mg (1million Units)

Pregnancy

Contraindicated. Use Only If Potential Benefit Outweighs Risk.

Stability

  • Antibacterials, Polymyxin

Contra Indications

  • Myasthenia Gravis

Precautions

  • Myasthenia Gravis

Lactation

  • Contraindicated, Avoid

Side Effects

  • Apnoea
  • Confusion
  • Headache
  • Muscle
  • Weakness
  • Nephrotoxicity
  • Perioral Paraesthesia
  • Peripheral Paraesthesia
  • Psychosis
  • Rash
  • Slurred Speech
  • Vertigo
  • Visual Disturbances.
  • Rare: Vasomotor Instability