Cycloserine
Therapeutic Group
Anti-mycobacterials (Anti-tuberculosis)Indication Dosage
Tuberculosis Resistant To First-line Drugs, In Combination with Other Drugs:
- Adult: Initially 250 Mg Every 12 Hours For 2 Weeks, Then Increased If Necessary Up To 500 Mg Every 12 Hours, Increased According To Blood Concentration And Response, For 18-24 Months (max Daily Dose 1 Gm).
- Children: 10-20 Mg/kg/day In 2 Divided Doses Up To 1000 Mg/day For 18-24 Months.
Content
- Cap /Tab: Cycloserine 250mg.
Pregnancy
Caution Advised, Use Only If Potential Benefit Outweighs Risk
Stability
- Antimycobacterial
Contra Indications
- Acute Porphyria, Alcohol Dependence, Depression, Epilepsy, Psychotic States, Severe Anxiety
Precautions
- Acute Porphyria, Alcohol Dependence, Depression, Epilepsy, Psychotic States, Severe Anxiety
Lactation
- Caution Advised
Side Effects
- Allergic Dermatitis
- Changes In Liver Function Tests
- Confusion
- Convulsions
- Depression
- Dizziness
- Drowsiness
- Headache
- Heart Failure At High Doses
- Megaloblastic Anaemia
- Psychosis
- Rashes
- Tremor
- Vertigo Cardiac Arrhythmias
- Paresis
- Coma.