Dalteparin Sodium

Therapeutic Group

Anti-thrombotic Agents

Indication Dosage

Dalteparin Sodium is a medication used to prevent blood clots. It's often prescribed to people who are at risk of clots, like those having surgery or recovering from certain medical conditions. It helps keep the blood flowing smoothly and reduces the chances of dangerous clots forming in your veins. Your doctor will prescribe it when they think it's necessary to protect your health.

Pre-operative Or Post-operative Surgical Thromboprophylaxis: 

By Sc Inj: 

  • Adult: 2500 Iu By Sc Inj Into Abdominal Wall Or Lateral Part Of Thigh 1 To 2 Hr Pre-op., Then 2500 Iu Daily Until Fully Mobile (generally 5-7 Days Or Longer). 

Prolonged Thromboprophylaxis In Hip Replacement Surgery Or High-Risk Surgery: 

By Sc Inj: 

  • Adult: 5000 Iu By Sc Inj On The Evening Before Surgery, Then 5000 Iu Each Evening For the Next 5 Weeks. 

Prevention Of Clotting In Extracorporeal Circulation During Haemodialysis Or Haemolittration: 

By Sc Inj: 

  • Adults: If No Additional Bleeding Risk, 30-40 Iu/kg By IV bolus Then 10-15 Iu/kg/hr by IV Infusion, Alternatively, If the Procedure is Less Than 4 Hr, As Above, Or 5000 Iu By IV bolus. If High Bleeding Risk, 5-10 Iu/kg By IV bolus Then 4-5 Iu/kg/hr by IV Infusion. 

Treatment Of Deep Venous Thrombosis And/ or Pulmonary Embolism: 

By Sc Inj: 

  • Adults: If No Additional Bleeding Risk, 200 Iu/ Kg by Sc Inj As A Single Daily Dose: Max 18000 Iu Daily. If High Bleeding Risk, 100 Iu/kg By Sc In Twice Daily. Give Anticoagulants Concurrently, and Use Combined Treatment For a Minimum of 5 Days. 

Unstable Coronary Artery Disease: 

By Sc Inj: 

  • Adults: 120 Iu/kg Sc Inj Every 12 Hr For 5-8 Days: Max 10000 Iu/12 Hr, Along With Low Dose Aspirin.

Content

  • Inj 2500 Iu /5000 Iu /7500 Iu /10000 1u: Dalteparin Sodium 2500 Iu (02 M14 /5000 111 (02 ml) /7500 Iu (0.3ml) /10000 10 (1 ml): Solution; Pre-Filled Syringe.

Pregnancy

No Evidence Of Risk In Humans.

Stability

  • Antithrombotic: Low Molecular Weight Heparin (lmwh)

Contra Indications

  • Do Not Initiate Therapy Within First Few Days After Mi. Ptca (stenting), Cabg Acute Ischaemic Stroke Of Less Than 7 Days, Hypoprothrombinaemia, Severe Hepatic Impairment, Bleeding Dis-orders, Active Bleeding Such As Peptic Ulcer Or Intracranial Haemorrhage.

Precautions

  • Do Not Initiate Therapy Within First Few Days After Mi. Ptca (stenting), Cabg Acute Ischaemic Stroke Of Less Than 7 Days, Hypoprothrombinaemia, Severe Hepatic Impairment, Bleeding Dis-orders, Active Bleeding Such As Peptic Ulcer Or Intracranial Haemorrhage.

Lactation

  • Caution Advised or Effect Undetermined.

Side Effects

  • Bleeding At High Doses. Heparin Like Side-effects.

Available Brands