Dobutamine

Therapeutic Group

Cardiac Therapy

Indication Dosage

Dobutamine is a medication primarily indicated for the short-term treatment of heart failure, particularly in cases where the heart's pumping ability is compromised. It is commonly used in hospital settings to increase cardiac output and improve blood flow in individuals experiencing acute heart failure or those undergoing certain cardiac diagnostic procedures. Dobutamine works by stimulating the heart muscles to pump more effectively, helping to alleviate symptoms of heart failure such as breathlessness and fluid retention. 

Inotropic Support In Infarction, Cardiac Surgery, Cardiomyopathies, Septic Shock, Cardiogenic Shock, And During Positive End Expiratory Pressure Ventilation: 

By IV Infusion: 

  • Adult: 2.5-10 Mcg/kg/min, Adjusted According To Response, Alternatively0.5-40 Mcg/kg/min 
  • Children: Neonate, Initially 5 Mcg/kg/minute Continuous IV Infusion Adjusted According To Response To 2-15 Mcg/ Kg/minute; Max. 20 Mcg/kg/minute; 1 Mth-18 Yr, Initially 5 Mcg/kg/minute Adjusted According To Response To 2-20 Mcg/kg/minute. 

Cardiac Stress Testing: 

By IV Infusion: 

  • Adult: Consult Product Literature.

Content

  • Inj 50mg: Per ml: Dobutamine 50mg; 250mg (5 ml)asdobutamine Hci.
  • Inj 12.5mg: Per ml: Dobutamine 12.5mg; 250mg(20 ml) As Dobutamine Hci, 1mg(1 ml) As Dobutamine Hci.

Pregnancy

Caution Advised

Stability

  • Sympathomimetics Inotropic Beta 1-agonist

Contra Indications

  • Pheochromocytoma.

Precautions

  • Pheochromocytoma.

Lactation

  • Caution Advised

Side Effects

  • Nausea; Hypotension
  • Hypertension
  • Arrhythmias
  • Palpitations
  • Chest Pain; Dyspnoea
  • Bronchospasm; Headache; Fever; Increased Urinary Urgency; Eosinophilia; Rash
  • Phlebitis; Very Rarely Myocardial Infarction
  • Hypokalaemia: Coronary Artery Spasm And Thrombocytopenia Also Reported.