Empagliflozin And Metformin HCI

Therapeutic Group

Blood Glucose Lowering Drugs, Excluding Insulin

Indication Dosage

Empagliflozin and Metformin HCl are medications used together to help lower blood sugar levels in adults with type 2 diabetes. They work by improving the way your body uses insulin and removing excess sugar from your bloodstream, helping you manage your diabetes better.

Type 2 Diabetes Mellitus Not Controlled By Metformin Alone Or By Metformin In Combination With Other Antidiabetic Drugs Or Insulin

Dosage:

Adult 18-84 Years: 5/850-5/1000 Mg Twice Daily, Increased If Necessary To 12.5/850-12.5/1000 Mg Twice Daily
Adult 85 Years And Over: Initiation Not Recommended

Content

Tab 5mg /1000mg: Empagliflozin 5mg And Metformin Hci 1000mg,
Tab 12.5mg /500mg: Empagliflozin 12.5mg And Metformin Hci 500mg,
Tab 12.5mg /1000mg: Empagliflozin 12.5mg And Metformin Hci 1000mg

Pregnancy

Advised To Avoid

Stability

Sodium Glucose Co-transporter 2 Inhibitors (sglt2)
Biguanide

Contra Indications

Diabetic Ketoacidosis, Severe Hepatic Impairment, Severe Renal Impairment, Acute Conditions Predisposing To Renal Impairment, Acute Metabolic Acidosis Or Pre-coma, Cardiac Or Respiratory Failure, Recent Mi, Alcoholism, Pregnancy, Lactation, And Elderly (above 75yrs)

Precautions

Diabetic Ketoacidosis, Severe Hepatic Impairment, Severe Renal Impairment, Acute Conditions Predisposing To Renal Impairment, Acute Metabolic Acidosis Or Pre-coma, Cardiac Or Respiratory Failure, Recent Mi, Alcoholism, Pregnancy, Lactation, And Elderly (above 75yrs)

Lactation

Advised to Avoid

Side Effects

Genital Infection
Hypoglycaemia (in Combination With Insulin Or Sulfonylurea)
Polyuria
Pruritus
Urinary Tract Infection
Dysuria
Volume Depletion (rare). Reports Of Altered Lfts
Hepatitis
Gi Upset
Taste Disturbance
Skin Reactions
Reduced B12 Absorptions
Abnormal Liver Function Tests
Rarely Lactic Acidosis