Enoxaparin
Therapeutic Group
Anti-thrombotic AgentsIndication Dosage
Enoxaparin is a medication used to prevent blood clots in people who are at risk of developing them. It's commonly prescribed to:
- Prevent Deep Vein Thrombosis (DVT): If you're going to have surgery, especially hip or knee replacement, or if you're bedridden due to illness, enoxaparin can help prevent dangerous blood clots in your legs.
- Prevent Pulmonary Embolism (PE): Enoxaparin is also used to reduce the risk of blood clots traveling to your lungs, which can be life-threatening.
- Manage Certain Heart Conditions: In some cases, enoxaparin is used to manage certain types of heart conditions, like unstable angina and non-Q-wave myocardial infarctions.
Prophylaxis Of Venous Thromboembolism Associated With General Surgery, Low Risk:
By Deep Sc Inj:
- Adult: 20 Mg By Deep Sc Injection 2 Hrs Pre-op, Than 20 Mg Once Daily For 7-10 Days Or Until Risk.
Orthopedic Surgery, High Risk:
By Deep Sc Inj:
- Adult: 40 Mg By Deep Sc Injection 12 Hrs Pre-op, Then 40 Mg Once Daily For 7- I0 Days Or Until Risk.
Prophylaxis In Acute Illness And For Bed-ridden Patients:
By Deep Sc Inj:
- Adult: 40mg By Deep Sc Injection 12 Hrspre-op, Then 40 Mg Once Daily For a minimum of 6 Days And Continue Until full Ambulation; Max 14 Days.
Treatment Of Deep Venous Thrombosis, Pulmonary Embolism:
By Deep Sc Inj:
- Adult: 1.5 Mg/kg by Sc Inj Daily For a Minimum of 5 Days Or Until Adequate Oral Anticoagulants are established. Treatment Of Unstable Angina And Non-q Wave Mi: 1 Mg/kg By Sc Inj Every 12 Hr For a Minimum of 2 Days Or Until Clinical Stabilization, Usually 2-8 Days Along with Oral Aspirin, 100-325 Mg Once Daily.
Prevention Of Thrombus Formation In The Extracorporeal Circulation During Haemodialysis:
By Deep Sc Inj:
- Adult: 1 Mg/kg Into Arterial Line Of Circuit Prior To Session. A Further Dose Of 0.5-1 Mg/kg May Be Given If the Session Exceeds 4 Hr. If High Risk Of Haemorrhage, 0.5mg/kg For Double Vascular Access Or 0.75 Mg/kg For Single Vascular Access
- Children: Not Recommended.
Content
- Inj 20mg /40mg /60mg /80mg /100mg: Per Single Dose Pre-Filled Syringe Enoxaparin: 20mg Equiv To 2000 Iu (0.2 ml), 40mg Equiv To 4000 Iu (0.4 ml), 60mg Equiv To 6000 Iu (0.6 ml), 80mg Equiv To 8000 Iu (0.8 ml), 100mg Equiv To 10000 Iu (0.10 ml)
Pregnancy
Caution Advised
Stability
- Antithrombotic: Low Molecular Weight Heparin (lmwh)
Contra Indications
- Acute Bacterial Endocarditis, Major Bleeding Disorders, Increased Risk Of Haemorrhage. Thrombocylopenia, Active Peptic Ulcer, Haemorrhagic Cva
Precautions
- Acute Bacterial Endocarditis, Major Bleeding Disorders, Increased Risk Of Haemorrhage. Thrombocylopenia, Active Peptic Ulcer, Haemorrhagic Cva
Lactation
- Caution Advised
Side Effects
- Bleeding gums
- Coughing up blood
- Difficulty with breathing or swallowing
- Headache
- Increased menstrual flow or vaginal bleeding
- Nosebleeds
- Paralysis
- Prolonged bleeding from cuts
- Nausea