Esomeprazole

Therapeutic Group

Nsaid-Associated Gastric Ulcer:

Adult By Iv Inj, Or By Infusion: 20 Mg Once Daily For 4-8 Weeks.
Adult: 20 Mg Daily Continue Until Oral Administration Possible, Injection To Be Given Over At Least 3 Minutes.

Prophylaxis Of Nsaid-Associated Gastric Or Duodenal Ulcer:

Adult By Iv Inj, Or By Infusion: 20 Mg Daily Continue Until Oral Administration Possible, Injection To Be Given Over At Least 3 Minutes.

Gastro-oesophageal Reflux Disease (in The Presence Of Erosive Reflux Oesophagitis):

Child 1-11 Years (body weight 10 Kg And Above): 10 Mg Once daily for 8 Weeks.
Child Above 12yrs And Adults: Initially 40 Mg Once Daily For 4 Weeks, Continued For Further 4 Weeks If Symptoms Persist; Maintenance 20 Mg Daily.
Adult By Iv Inj, Or By Infusion: 40 Mg Daily Continue Until Oral Administration Possible, Injection Over At Least 3 Minutes.

Symptomatic Treatment Of Gastro-oesophageal Reflux Disease Gord (in The Absence Of Oesophagitis):

Child 1-11 Years (body weight 10 Kg And Above): 10 Mg Once Daily For Up To 8 Weeks
Children Above 12yrs And Adults: 20 Mg Once Daily For Up To 4 Weeks, Continue For a Further 4 Wks If Required.
Adult By Iv Inj, Or By Infusion: 20 Mg Once Daily Continue Until Oral Administration Is Possible, Injection To Be Given Over At Least 3 Minutes.

Zollinger-Ellison Syndrome:

Adult: 40 Mg Twice Daily, Adjusted According To Response; Usual Dose 80-160 Mg Daily.

Severe Peptic Ulcer Bleeding (following Endoscopic Treatment):

Adult By Infusion: 80 Mg, To Be Given Over 30 Minutes, Then (by Continuous Intravenous Infusion) 8 Mg/hour For 72 Hours, Then (by Mouth) 40 Mg Once Daily For 4 Wks.

Helicobacter Pylori Eradication In Combination With Clarithromycin And Amoxicillin Or Metronidazole:

Use Only If Clearly Needed