Esomeprazole And Sodium Bicarbonate
Therapeutic Group
Peptic Ulcer & Gastro-Oesophageal Reflux DiseaseIndication Dosage
Reflux Oesophagitis:
- Adults: 20 Mg Once Daily For 4 Wk, Extend For A Further 4-8 Weeks If Not Fully Healed.
Refractory Cases:
- Adults: 40 Mg Once Daily.
Acid-reflux Disease:
- Adults: Long-term Management, 10 Mg Once Daily, Increased To 20 Mg Once Daily If Symptoms Return.
Benign Duodenal Ulceration:
- Adults: 20 Mg Once Daily For 4 Weeks. Severe Cases; Increased To 40 Mg Once Daily.
Prevention Of Relapse:
- Adults: 10 Mg Once Daily, Increasing To 20 Mg Once Daily If Symptoms Return.
Duodenal Ulceration With Helicobacter Pylori:
- Adults: 40 Mg Daily With Amoxicillin 1.5-2 Gm Daily For 2 Weeks.
Benign Gastric Ulceration:
- Adults: 20 Mg Once Daily For 8 Wk. Severe Cases: Increase To 40 Mg Once Daily.
Zollinger-Ellison Syndrome:
- Adults: 60 Mg Once Daily Adjusted To Response.
- Usual Maintenance: 20-120 Mg Daily. Doses Over 80 Mg Daily Are Given In Two Divided Doses
Acid Aspiration:
- Adults: 40 Mg In The Evening Of The Day Before Surgery, Then 40 Mg 1-4 hours prior To Surgery.
- Children: Not Recommended.
Content
- Cap 20 Mg/1100 mg: Esomeprazole 20 mg and Sodium Bicarbonate 1100 Mg.
- Cap 40 Mg/1100 mg: Esomeprazole 40 mg And Sodium Bicarbonate 1100 mg.
Pregnancy
Risk Cannot Be Ruled Out.
Stability
- Antacid
- Proton Pumps Inhibitor (PPI)
Contra Indications
- Known
Precautions
- Known
Lactation
- Not Recommended
Side Effects
- Headache
- Somnolence
- Insomnia
- Arthralgia
- Gi Upset
- Skin Rashes
- Paraesthesia
- Dizziness
- Myalgia
- Increased Risk Of Gi Infections
- Increase In Liver Enzymes.