Exemestane

Therapeutic Group

Endocrine Hormone Therapy

Indication Dosage

Exemestane is a medication primarily indicated for the treatment of postmenopausal women with hormone receptor-positive early breast cancer after they have completed 2-3 years of tamoxifen therapy. It is also prescribed for postmenopausal women with advanced breast cancer whose disease has progressed following anti-estrogen therapy. Exemestane works by reducing the production of estrogen in the body, thereby helping to slow down the growth of hormone-sensitive breast tumors. 

Adjuvant Treatment Of Oestrogen-receptor-positive Early Breast Cancer In Postmenopausal Women Following2-3 Years Of Tamoxifen Therapy, Advanced Breast Cancer in Postmenopausal Women In Whom Anti-oestrogen therapy Has Failed: 

  • Adult: 25 Mg Daily After A Meal. In Early Breast Cancer, Continue Treatment Until Completion Of 5 Yr Combined Sequential Adjuvant Therapy With Tamoxifen, Or Earlier If the Tumour Relapses. In Advanced Breast Cancer Continue Treatment Until Subsided. 
  • Children: Not Recommended.

Content

  • Tab 25mg: Exemestane 25mg.

Pregnancy

Contraindicated In Pregnancy.

Stability

  • Aromatase Inhibitor

Contra Indications

  • Pre-menopausal Women.

Precautions

  • Pre-menopausal Women.

Lactation

  • Contraindicated. Discontinue Breast-feeding.

Side Effects

  • Abdominal Pain
  • Alopecia
  • Anorexia
  • Constipation
  • Depression
  • Dizziness
  • Dyspepsia
  • Fatigue
  • Headache
  • Hot Flushes
  • Insomnia
  • Nausea
  • Rash
  • Sweating
  • Vomiting
  • Asthenia
  • Drowsiness
  • Peripheral Oedema.
  • Rare: Leucopenia
  • Thrombocytopenia

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