Fludarabine Phosphate
Therapeutic Group
Anti-neoplasticsIndication Dosage
Fludarabine Phosphate is a medication used to treat certain types of cancer, specifically chronic lymphocytic leukemia (CLL) in adults. It works by slowing down the growth of cancer cells, helping to manage the disease and improve the patient's quality of life.
Initial Treatment Of Advanced B-cell Chronic Lymphocytic Leukaemia (cll), First-line Treatment In Patientswith Sufficient Bone-marrow Reserves:
By IV Inj:
- Adult: 50 Mg Daily For 5 Days Every 28 Days, Usually Givenfor 6 Cycles. See Product Literature
- Children: Not Recommended.
Content
- Inj 50mg: Fludarabine Phosphate 50mg; Powder In Vial,
Pregnancy
Positive Evidence Of Risk: Avoid
Stability
- Antimetabolite
Contra Indications
- Haemolytic Anaemia
Precautions
- Haemolytic Anaemia
Lactation
- Contraindicated. Discontinue Breast-feeding.
Side Effects
- Acutemyeloid
- Leukaemia
- anorexia
- Chills
- Cough
- Diarrhoea
- Fever
- Immunosuppression
- Malaise
- Myelodysplastic Syndrome
- Myelosupression
- Oedema
- Peripheral Neuropathy
- Pneumonia
- Rash
- Visualdisturbances
- Weakness
- Autoimmune Disorder
- Confusion
- Fibrosis
- haemorrhage
- Immune-mediated Haemolytic Anaemia
- neutropenia
- Pneumonitis
- Pulmonary Toxicity
- Thrombocytopenia
- Alopecia
- Bone-marrow Suppression
- Extravasation
- Haemorrhagic Cystitis
- Hyperuricaemia
- Nausea
- Oral Mucositis
- Thromboembolism
- Tumourlysis Syndrome
- Vomiting.
- Rare: Agitation
- Arrhythmia
- Blindness
- Coma
- Heart Failure
- Optic Neuropathy
- Seizures
- Skin Cancer
- Stevens-Johnson Syndrome
- Toxic Epidermal Necrolysis