Glimepiride And Metformin

Therapeutic Group

Blood Glucose Lowering Drugs, Excluding Insulin

Indication Dosage

Therapy For Type 2 Diabetes Mellitus: 

  • Adults: 1 Mg Glimepiride And Metformin Hci 500 Mg Daily; Maintenance Dose 1 Mg To 4 Mg Glimepiride Daily. Max: Glimepiride 8 Mg, Metformin Hci 2000 Mg. The Dosage Is Administered According To Individual Requirements. 
  • Children: Not Recommended

Content

  • Tab 1 /500mg: Glimepiride 1mg, Metformin Hci 500mg.
  • Tab 2 /500mg: Glimepiride 2mg, Metformin Hci 500mg.
  • Tab 1 /250mg: Glimepiride 1mg, Metformin Hci 250mg.

Pregnancy

Contraindicated

Stability

  • Biguanide
  • Sulphonylurea

Contra Indications

  • Insulin-dependent Diabetes, Diabetic Ketonaemia, Coma/precoma, Metabolic Acidosis, Lactic Acidosis, Congestive Heart Failure, Severe Infections, Recent Surgery, Serious Trauma, Malnourished, Starving Or Debilitated Patients, Pituitary/ Adrenal In Sufficiency, Severe Lung Dysfunction, Hypoxaemia, Hepatic Dysfunction, Alcoholism, Dehydration, Gi Disturbances, Iodinated Contrast Iv, Hypersensitivity To Sulfonylureas, Sulphonamides Or Biguanides,

Precautions

  • Insulin-dependent Diabetes, Diabetic Ketonaemia, Coma/precoma, Metabolic Acidosis, Lactic Acidosis, Congestive Heart Failure, Severe Infections, Recent Surgery, Serious Trauma, Malnourished, Starving Or Debilitated Patients, Pituitary/ Adrenal In Sufficiency, Severe Lung Dysfunction, Hypoxaemia, Hepatic Dysfunction, Alcoholism, Dehydration, Gi Disturbances, Iodinated Contrast Iv, Hypersensitivity To Sulfonylureas, Sulphonamides Or Biguanides,

Lactation

  • Contraindicated or Not Recommended

Side Effects

  • Hypoglycaemia
  • Temporary Visual Impairment
  • Metallic Taste
  • Rash
  • Subnormal Vit B12 Levels
  • Gi Disturbances
  • Liver Impairment

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