Glimepiride And Pioglitazone
Therapeutic Group
Blood Glucose Lowering Drugs, Excluding InsulinIndication Dosage
Type 2 Diabetes Not Controlled By Metformin Alone, Particularly In Obese:
- Adults: One Tab Of 30 Mg/2 Mg Once Daily Or 15 Mg/4 Mg Once Daily, (the Dosage Of Glimepiride Is To Be Reduced In Case Of Hypoglycaemia). The Dosage Can Be Increased To 30 Mg/4 Mg Once Daily.
- Children: Not Recommended.
Content
- Tab 15 /1mg: Pioglitazone 15mg, Glimepiride 1mg.
- Tab 15 /2mg: Pioglitazone 15mg, Glimepiride 2mg.
- Tab 15 /4mg: Pioglitazone 15mg, Glimepiride 4mg,
- Tab 30 /2mg: Pioglitazone 30mg, Glimepiride 2mg,
Pregnancy
Contraindicated Or Not Recommended
Stability
- Sulphonylurea
- Thiazolidinedione
Contra Indications
- History Of Heart Failure, Previous Or Active Bladder Cancer, Uninvestigated Macroscopic Haematuria, Dialysis, Diabetic Ketoacidosis, Pregnancy And Lactation.
Precautions
- History Of Heart Failure, Previous Or Active Bladder Cancer, Uninvestigated Macroscopic Haematuria, Dialysis, Diabetic Ketoacidosis, Pregnancy And Lactation.
Lactation
- Contraindicated or Not Recommended.
Side Effects
- Gi Disturbances
- Anaemia
- Arthralgia
- Dizziness
- Haematuria
- Headache
- Hypoaesthesia
- Impotence
- Oedema
- Vertigo
- Visual Disturbances
- Weight Gain
- Altered Blood Lipids
- Bladder Cancer
- Fatigue
- Hypoglycaemia
- Insomnia
- Proteinuria
- Sweating.
- Rare: Liver Dysfunction.