Ibuprofen

Therapeutic Group

Anti-inflammatory And Anti-rheumatic Products

Indication Dosage

Pain And Inflammation In Rheumatic Disease And Other Musculoskeletal Disorders, Fever, Mild To Moderate Pain Including Dysmenorrhea, Postoperative Analgesia, Migraine, Dental Pain: 

  • Adult: Initially 300-400 Mg 3-4 Times A Day; Increased If Necessary Up To 600 Mg 4 Times A Day, Dose To Be Increased Only In Severe Cases; Maintenance 200-400 Mg 3 Times A Day 

Mild To Moderate Pain, Fever, Pain And Inflammation Of Soft-tissue Injuries, Pyrexia With Discomfort 

  • Adult & Child Above 12 years: Initially 300-400 Mg 3-4 Times A Day; Increased If Necessary Up To 600 Mg 4 Times A Day, Dose To Be Increased Only In Severe Cases; Maintenance 200-400 Mg 3 Times A Day 
  • Children 3-5 Months: 50 Mg 3 Times A Day, Maximum30 Mg/kg Per Day; 
  • 6-11 Months: 50 Mg 3-4 Times A Day, Maximum30 Mg/kg Per Day; 
  • 1-3 Years: 100 Mg 3 Times A Day, Maximum30 Mg/kg Per Day; 
  • 4-6 Years: 150 Mg 3 Times A Day, Maximum30 Mg/kg Per Day; 
  • 7-9 Years: 200 Mg 3 Times A Day, Maximum30 Mg/kg Per Day; Maximum 2.4 G Per Day; 
  • 10-11 Years: 300 Mg 3 Times A Day, Maximum30 Mg/kg Per Day; Maximum 2.4 G Per Day 

Pain And Inflammation In Rheumatic Disease Including Systemic Juvenile Idiopathic Arthritis: 

  • Children 3 Months - 17 Years: 30-40 Mg/kg Daily In 3-4 Divided Doses; Increase Up To 60 Mg/kg Daily In 4-6 Divided Doses; Maximum 2.4 G Per Day 

Post-immunisation Pyrexia In Infants: 

  • Children 2-3 Months: 50 Mg For 1 Dose, Followed By 50 Mg After 6 Hours If Required

Content

  • Susp: Per 5 ml: Ibuprofen 100mg.
  • Tab 200mg /400mg /600mg /800mg: Ibuprofen 200mg /400mg /600mg /800mg.
  • Cap 100mg /200mg /400mg: Ibuprofen 100mg /200mg /400mg.

Pregnancy

Caution Advised, Risk Cannot Be Ruled Out.

Stability

  • Propionic Acid

Contra Indications

  • Active Or Recurrent Gi Bleeding Or Ulceration, Cerebrovascular Disease, History Of Gi Bleeding Or Gi Perforation Related To Previous Nsaid Therapy, History Of Recurrent Gi Haemorrhage, Ischaemic Heart Disease, Heart Failure, Peripheral Arterial Disease, Moderate To Severe Renal Impairment, Aspirin/anti-inflammatory Induced Allergy.

Precautions

  • Active Or Recurrent Gi Bleeding Or Ulceration, Cerebrovascular Disease, History Of Gi Bleeding Or Gi Perforation Related To Previous Nsaid Therapy, History Of Recurrent Gi Haemorrhage, Ischaemic Heart Disease, Heart Failure, Peripheral Arterial Disease, Moderate To Severe Renal Impairment, Aspirin/anti-inflammatory Induced Allergy.

Lactation

  • Caution Advised

Side Effects

  • Angioedema
  • Blood Disorders
  • Bronchospasm
  • Colitis
  • Crohn's Disease
  • Depression
  • Diarrhoea
  • Dizziness
  • Drowsiness
  • Fluid Retention
  • Gi Bleeding And Ulceration
  • Gi Disturbances
  • Haematuria
  • Headache
  • Hearing Disturbances
  • Hypersensitivity Reactions
  • Insomnia
  • Nausea
  • Nervousness
  • Photosensitivity
  • Raised Blood Pressure
  • Rashes
  • Renal Failure (especially In Patients With Preexisting Renal Impairment)
  • tinnitus
  • Vertigo.
  • Rare: Hepatic Damage
  • Interstitial Fibrosis Associated With Nsaids
  • Stevens-johnson Syndrome
  • Toxic Epidermal Necrolysis
  • Visual Disturbances
  • Exacerbation Of Symptoms In Asthma
  • Thrombo-cytopenia
  • Aseptic Meningitis

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