Indomethacin
Therapeutic Group
Anti-inflammatory And Anti-rheumatic ProductsIndication Dosage
Pain And Moderate To Severe Inflammation In Rheumatic Disease, Osteoarthritis, And Other Musculoskeletal Disorders, Serious Musculoskeletal Injuries:
Oral:
- Adult & Children: 50-200 Mg Daily In Divided Doses
By Rectum:
- Adult: 100 Mgsuppository Twice Daily If Required, Dose To Be administered At Night And In The Morning, Combined oral And Rectal Treatment, Maximum Total Daily Dose 150-200mg
Acute Gout:
Oral:
- Adult & Children: 150-200 Mg Daily In Divided Doses
By Rectum:
- Adult: 100 Mg Suppository Twice Daily If Required, Dose To Be administered At Night And In The Morning, Combined oral And Rectal Treatment, Maximum Total Daily Dose 150-200mg
Dysmenorrhoea:
Oral:
- Adult & Children: Up To 75 Mg Daily
By Rectum:
- Adult: 100 Mg Suppository Twice Daily If Required, Dose To Beadministered At Night And In The Morning, Combined oral And Rectal Treatment, Maximum Total Daily Dose150-200mg
Content
- Tab 25mg /75mg: Indomethacin 25mg /75mg.
- Cap 25mg /50mg /75mg: Indomethacin 25mg /50mg /75mg.
- Suppository 50mg /100mg: Indomethacin 50mg /100mg
Pregnancy
Contraindicated In Pregnancy.
Stability
- Nsaid: Indole
Contra Indications
- Active Gi Bleeding And Ulceration, History Of Gibleeding Or Perforation Related To Previous Nsaid Therapy, History Of Recurrent Gi Haemorrhage Or Ulceration (two Or More Distinct Episodes), Severe Heart Failure, History Of Git Lesions, Aspirin Or Anti-inflammatory Drug-induced Allergy.
Precautions
- Active Gi Bleeding And Ulceration, History Of Gibleeding Or Perforation Related To Previous Nsaid Therapy, History Of Recurrent Gi Haemorrhage Or Ulceration (two Or More Distinct Episodes), Severe Heart Failure, History Of Git Lesions, Aspirin Or Anti-inflammatory Drug-induced Allergy.
Lactation
- Contraindicated
Side Effects
- Angioedema
- Blood Disorders
- Bronchospasm
- Colitis
- Crohn's Disease
- Depression
- Diarrhoea
- Dizziness
- Drowsiness
- Fluid Retention
- Gi Bleeding And Ulceration
- Gi Disturbances
- Haematuria
- Headache
- Hearing Disturbances
- Hypersensitivity Reactions
- Insomnia
- Nausea
- Nervousness
- Photosensitivity
- Raised Blood Pressure
- Rashes
- Renal Failure (especially In Patients With Preexisting Renal Impairment)
- tinnitus
- Vertigo.
- Rare: Hepatic Damage
- Interstitial Fibrosis Associated With Nsaids
- Stevens-johnson Syndrome
- Toxic Epidermal Necrolysis
- Visual Disturbances
- Exacerbation Of Symptoms In Asthma
- Thrombocytopenia
- Aseptic Meningitis