Ketoprofen

Therapeutic Group

Anti-inflammatory And Anti-rheumatic Products

Indication Dosage

Pain And Mild Inflammation In Rheumatic Disease: 

Relief Of Pain In Musculoskeletal Disorders, Pain After Orthopaedic Surgery, Dysmenorrhoea, Acute Gout, Treatment In Knee Or Hand Osteoarthritis (adjunct): 

Oral: 

  • Adults: 200 Mg Daily Either Divided into two Doses Or As A Single Dose. 
  • Children: Not Recommended. 

By Deep IM Inj: 

  • Adults: 50-100 Mg Every 4 Hr. Max: 200 Mg Daily For 3 Days. 
  • Children: Not Recommended. 

Adhesive Patch: 

  • Adults: One Patch Applied 12 Hourly At The Site Of Pain. 
  • Children: Not Recommended.

Content

  • Cap 100mg /200mg: Ketoprofen 100mg /200mg.
  • Tab 25mg /100mg /200mg: Ketoprofen 25mg /100mg /200mg.
  • Inj: Per ml: Ketoprofen 50mg; 2 ml Amp.
  • Adhesive Patch: Adhesive Patch Containing 30mg Ketoprofen.

Pregnancy

Avoid, Especially During The Third Trimester

Stability

  • Propionic Acid

Contra Indications

  • Severe Renal Dysfunction, Active Peptic Ulcer Or History Of Recurrent Peptic Ulceration, Asthma, Aspi-rin/anti- Inflammatory Induced Allergy, Active Gi Bleeding, History Of Gi Bleeding, History Of Gi Perforation, Severe Heart Failure

Precautions

  • Severe Renal Dysfunction, Active Peptic Ulcer Or History Of Recurrent Peptic Ulceration, Asthma, Aspi-rin/anti- Inflammatory Induced Allergy, Active Gi Bleeding, History Of Gi Bleeding, History Of Gi Perforation, Severe Heart Failure

Lactation

  • Caution Advised

Side Effects

  • Angioedema
  • Blood Disorders
  • Bronchospasm
  • Colitis
  • Crohn's Disease
  • Depression
  • Diarrhoea
  • Dizziness
  • Drowsiness
  • Fluid Retention
  • Gi Bleeding And Ulceration
  • Gi Disturbances
  • Haematuria
  • Headache
  • Hearing Disturbances
  • Hypersensitivity Reactions
  • Insomnia
  • Nausea
  • Nervousness
  • Photosensitivity
  • Raised Blood Pressure
  • Rashes
  • Renal Failure (especially In Patients With Preexisting Renal Impairment)
  • tinnitus
  • Vertigo.
  • Rare: Hepatic Damage
  • Interstitial Fibrosis Associated With Nsaids
  • Stevens-johnson Syndrome
  • Toxic Epidermal Necrolysis
  • Visual Disturbances
  • Exacerbation Of Symptoms In Asthma
  • Thrombocytopenia
  • Aseptic Meningitis