Magnesium Sulphate

Therapeutic Group

Magnesium sulfate, also known as Epsom salt, is a medication primarily indicated for its therapeutic use in the following conditions:

Magnesium Deficiency: Magnesium sulfate is administered to correct magnesium deficiencies in the body, which can occur due to various medical conditions, such as malnutrition or gastrointestinal disorders.
Pre-eclampsia and Eclampsia: It is used in obstetrics to manage and prevent pre-eclampsia (high blood pressure during pregnancy) and eclampsia (seizures in pregnant women).
Muscle Cramps and Spasms: Magnesium sulfate may be prescribed to alleviate muscle cramps and spasms, particularly in conditions like tetanus or after certain surgical procedures.
Constipation Relief: In some cases, it is used as a laxative to relieve occasional constipation.
Arrhythmias: Intravenous magnesium sulfate can be employed in the treatment of certain cardiac arrhythmias or irregular heart rhythms.
Migraine Headaches: It may be considered as part of a treatment regimen for acute migraine headaches in certain situations.
Topical Applications: Magnesium sulfate can be applied topically in the form of Epsom salt baths or poultices for muscle relaxation and pain relief.

Prevention Of Seizures In Pre-eclampsia:

By IV Inj:

Adult: Initially 4 G, To Be Given Over 5-15 Minutes, Followed By (by IV infusion) 1 Gram/hour For 24 Hours, If Seizure Occurs, an Additional Dose Of 2g By IV Injection To Be Administered; If Seizure Recurs, Increase The Infusion Rate To1.5-2 G/hour Or Give An Additional Dose Of 2g By IV Injection

Magnesium Deficiency And Hypomagnesaemia:

By IV Infusion, Or By IM Inj:

Adult: Up To 40 G, Given Over A Period Of Up To 5 Days, Dose Given Depends On The Amount Required To Replace The Deficit (allowing For Urinary Losses);
Maintenance: 2.5-5 G Daily, Usual Dose 3 G Daily

Emergency Treatment Of Serious Arrhythmias:

By IV Inj:

Adult: 2 G, To Be Given Over 10-15 Minutes, Dose May Be Repeated Once If Necessary

Myocardial Infarction:

By IV Inj, Iv Infusion:

Adults: Initially IV Injection Of 8 Mmol Magnesium Over 20 Min, Followed By IV Infusion Of 65-72m Molof Magnesium Over The Following 24 Hr.

Severe Acute Asthma, Continuing Respiratory Deterioration In Anaphylaxis:

By IV Infusion:

Adult: 1.2-2 G, To Be Given Over 20 Minutes
Children 2-17 Years: 40 Mg/kg (max. Per Dose 2 G), To Be Given Over 20 Minutes

Inj: Each ml Of The 50% Solution Contains 500mg Magnesium Sulphate Heptahydrate (approx 2 Mmol Magnesium Per ml).

Consult with Doctor Or Caution Advised