Magnessium Sulphate

Therapeutic Group

Indication Dosage

Magnesium sulfate, also known as Epsom salt, is a medication primarily indicated for its therapeutic use in the following conditions:

• Magnesium Deficiency: Magnesium sulfate is administered to correct magnesium deficiencies in the body, which can occur due to various medical conditions, such as malnutrition or gastrointestinal disorders.
• Pre-eclampsia and Eclampsia: It is used in obstetrics to manage and prevent pre-eclampsia (high blood pressure during pregnancy) and eclampsia (seizures in pregnant women).
• Muscle Cramps and Spasms: Magnesium sulfate may be prescribed to alleviate muscle cramps and spasms, particularly in conditions like tetanus or after certain surgical procedures.
• Constipation Relief: In some cases, it is used as a laxative to relieve occasional constipation.
• Arrhythmias: Intravenous magnesium sulfate can be employed in the treatment of certain cardiac arrhythmias or irregular heart rhythms.
• Migraine Headaches: It may be considered as part of a treatment regimen for acute migraine headaches in certain situations.
• Topical Applications: Magnesium sulfate can be applied topically in the form of Epsom salt baths or poultices for muscle relaxation and pain relief.

Prevention Of Seizures In Pre-eclampsia: 

By IV Inj: 

• Adult: Initially 4 G, To Be Given Over 5-15 Minutes, Followed By (by IV infusion) 1 Gram/hour For 24 Hours, If Seizure Occurs, an Additional Dose Of 2g By IV Injection To Be Administered; If Seizure Recurs, Increase The Infusion Rate To1.5-2 G/hour Or Give An Additional Dose Of 2g By IV Injection

Magnesium Deficiency And Hypomagnesaemia: 

By IV Infusion, Or By IM Inj: 

• Adult: Up To 40 G, Given Over A Period Of Up To 5 Days, Dose Given Depends On The Amount Required To Replace The Deficit (allowing For Urinary Losses); 
• Maintenance: 2.5-5 G Daily, Usual Dose 3 G Daily 

Emergency Treatment Of Serious Arrhythmias: 

By IV Inj: 

• Adult: 2 G, To Be Given Over 10-15 Minutes, Dose May Be Repeated Once If Necessary 

Myocardial Infarction: 

By IV Inj, Iv Infusion: 

• Adults: Initially IV Injection Of 8 Mmol Magnesium Over 20 Min, Followed By IV Infusion Of 65-72m Molof Magnesium Over The Following 24 Hr. 

Severe Acute Asthma, Continuing Respiratory Deterioration In Anaphylaxis: 

By IV Infusion: 

• Adult: 1.2-2 G, To Be Given Over 20 Minutes 
• Children 2-17 Years: 40 Mg/kg (max. Per Dose 2 G), To Be Given Over 20 Minutes

Content

Pregnancy

Consult with Doctor Or Caution Advised

Stability

Contra Indications

Precautions

Lactation

Side Effects