Meropenem

Therapeutic Group

Other Beta-Lactam, Cephalosporins & Penems

Indication Dosage

Aerobic And Anaerobic Gram-positive And Gram-negative Infections, Hospital-acquired Septicaemia: 

By IV Infusion, Or By IV Inj: 

  • Adult: 0.5-1 G Every 8 Hours 
  • Children Above 3 Months: 10- 20 Mg/kg By IV bolus Injection Over 5 Min Or By IV Infusion Over 15- 30 Min Every 8 Hr 

Exacerbations Of Chronic Lower Respiratory-tract Infection In Cystic Fibrosis: 

By IV Infusion, Or By IV Inj: 

  • Adult: 2 G Every 8 Hours 
  • Children Above 3 Months: 10- 20 Mg/kg By IV bolus Injection Over 5 Min Or By IV Infusion Over 15- 30 Min Every 8 Hr 

Meningitis, Endocarditis (in Combination With Another Antibacterial): 

By IV Infusion, Or By IV Inj: 

  • Adult: 2 G Every 8 Hours 
  • Children Above 3 Months: 40mg/kg By IV bolus Injection Over 5 Min Or By IV Infusion Over 15- 30 Min Every 8 Hr

Content

  • IV Inj 500mg /1gm: Meropenem 500mg /1gm; Powder In Vials.

Pregnancy

Avoid Unless Potential Benefit Outweighs Risk.

Stability

  • Antibiotic, Carbapenem

Contra Indications

  • None Known

Precautions

  • None Known

Lactation

  • Caution Advised, Avoid

Side Effects

  • Abdominal Pain
  • Diarrhoea
  • Disturbances In Liver Function Tests
  • Headache
  • Nausea
  • Pruritus
  • Rash
  • Thrombocythaemia
  • Vomiting
  • Eosinophilia
  • Leucopenia
  • Paraesthesia
  • Thrombocytopenia
  • Convulsions
  • Antibiotic-associated Colitis
  • Haemolytic Anaemia
  • Stevens-johnson Syndrome
  • Toxic Epidermal Necrolysis